MoenomycinComplex , ≥98% , 11015-37-5

CAS NO.：11015-37-5

Empirical Formula: C69H107N4O35P

Molecular Weight: 1583.57

MDL number: MFCD01742468

EINECS: 234-246-7

PRODUCT Properties

• Melting point: >150° (dec.)
• storage temp.: 0-6°C
• solubility: Water (Slightly)
• form: Solid
• color: Dark Brown
• InChIKey: PERZMHJGZKHNGU-XIGAONJHSA-N
• LogP: 1.983 (est)
• CAS DataBase Reference: 11015-37-5
• EPA Substance Registry System: Bambermycin (11015-37-5)

Description and Uses

Moenomycin complex is a mixture of moenomycins A, A₁₂, C₁, C₃ and C₄, which are antibiotics isolated from several strains of Streptomyces that directly inhibit bacterial peptidoglycan glycosyltransferases. The minimal inhibitory concentration of moenomycin A against various Gram-positive bacteria ranges from 1-100 nM.

Moenomycin complex is a mixture of five major components, A, A12, C1, C3 and C4, isolated from several strains of Streptomyces in the 1960s. Moenomycins are high molecular weight phosphoglycolipids with potent antibiotic activity used in animal health. Moenomycins are the only antibiotic known to selectively inhibit the transglycosylation step catalysed by penicillin-binding protein 1b.

Safety

• Hazard statements: H413
• Risk Statements: 53
• RIDADR: UN 3077 9 / PGIII
• WGK Germany: 1
• RTECS: QA3020000
• Toxicity: LD50 in mice (mg/kg): >2000 orally, s.c. and i.p.; 1400 i.v. (Lindner, Wallhuser)