LN-889916
RP107 , 95% , 496864-16-5
Synonym(s):
Aloisine A - CAS 496864-16-5 - Calbiochem;RP107, 7- n-Butyl-6-(4-hydroxyphenyl)[5H]pyrrolo[2,3-b]pyrazine
Update time: 2023-04-23
PRODUCT Properties
| Melting point: | 281-283°C |
| Density | 1.227 |
| storage temp. | Keep in dark place,Sealed in dry,2-8°C |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Yellow solid |
| pka | 9.67±0.15(Predicted) |
| color | Light Orangish Yellow |
Description and Uses
A cell-permeable pyrrolo-pyrazine compound that acts as a potent, selective, reversible, and ATP-competitive inhibitor of cyclin dependent kinases (Cdks: IC50 =150nM, 120 nM, 400 nM and 200 nM for Cdk1/cyclin B, Cdk2/cyclin A, Cdk2/cyclin E, and Cdk5/p25,
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P305+P351+P338 |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36/37 |
