Vinblastine , 98% , 865-21-4
CAS NO.：865-21-4
Empirical Formula: C46H58N4O9
Molecular Weight: 810.99
MDL number: MFCD05662370
EINECS: 212-734-0
| Pack Size | Price | Stock | Quantity |
| 10MG | RMB399.20 | In Stock |
|
| 20mg | RMB606.40 | In Stock |
|
| 50MG | RMB1519.20 | In Stock |
|
| 250MG | RMB3591.20 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 211-216° |
| alpha | D23 -32° (c = 0.88 in methanol) |
| Boiling point: | 755.65°C (rough estimate) |
| Density | 1.1325 (rough estimate) |
| refractive index | 1.6000 (estimate) |
| storage temp. | Sealed in dry,Store in freezer, under -20°C |
| solubility | Chloroform, Dichloromethane, Dimethyl Sulfoxide, Methanol |
| form | Solid |
| pka | 5.4, 7.4(at 25℃) |
| color | Yellow |
| EPA Substance Registry System | Vinblastine (865-21-4) |
Description and Uses
An alkaloid derived from the periwinkle, Catharanthus roseus (formerly Vinca rosea) used as an antitumor drug in the treatment of Hodgkins lymphoma and other cancers. It binds to the microtubule subunit, tubulin, at a site distinct from that of colchicine and podophyllotoxin. This binding is reversible, temperature dependent and rapid, and results in large tubulin aggregates of highly ordered structure (vinblastine paracrystals).
Vinblastine is used for severe lymphoblastic leukemia, Hodgkin’s disease, nonHodgkin’s lymphoma, neuroblastoma, sarcoma, and other cancerous diseases.
Safety
| RIDADR | 1544 |
| HazardClass | 6.1(a) |
| PackingGroup | II |
| Hazardous Substances Data | 865-21-4(Hazardous Substances Data) |
| Toxicity | LD50 intraperitoneal in mouse: 3120ug/kg |
