Home Categories API Vincristine sulfate salt
A8352612

Vincristine sulfate salt , Analysis of standards,> 99% , 2068-78-2

Synonym(s):
22-Oxovincaleukoblastine sulfate salt;Leurocristine sulfate salt;V5 Tag Peptide;VCR;Vincristine sulfate salt

CAS NO.:2068-78-2

Empirical Formula: C46H58N4O14S

Molecular Weight: 923.04

MDL number: MFCD08706469

EINECS: 218-190-0

Pack Size Price Stock Quantity
10MG RMB422.40 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 300 °C
Boiling point: 273-281 °C
alpha  D26 +8.5° (c = 0.8)
storage temp.  Sealed in dry,Store in freezer, under -20°C
solubility  methanol: soluble20mg/mL
form  lyophilized powder
color  white to off-white
Water Solubility  >=1 g/100 mL at 24 ºC
BRN  3924631
Stability: Stable for 2 years from date of purchase as supplied. Solutions in distilled water may be stored at -20° for up to 3 months.
InChIKey AQTQHPDCURKLKT-HSMPTBRCNA-N

Description and Uses

Vincristine sulfate (2068-78-2) arrests cell cycle at G2/M by interfering with mitotic spindle formation. Depolymerizes microtubules and blocks binding of tubulin to microtubule proteins.1,2?Induces apoptosis.3?Vincristine sulfate is a clinically useful cancer chemotherapeutic agent.

Vincristine sulfate, is used as an anticancer agent, microtubule disrupter, Induces apoptosis in human lymphoma cells. Other applications include as a cell cycle arresting, apoptotic inducing alkaloid.

Safety

Symbol(GHS) 
GHS06,GHS08
Signal word  Danger
Hazard statements  H300-H341-H361fd
Precautionary statements  P202-P264-P270-P280-P301+P310-P405
Hazard Codes  T
Risk Statements  61-36/37/38-63-23/24/25-68-62-25
Safety Statements  22-24/25-53-45-37/39-26-36/37/39-36/37
RIDADR  UN 2811 6.1/PG 2
WGK Germany  3
RTECS  OH6340000
8-10
HazardClass  6.1(a)
PackingGroup  II
HS Code  29399990
Toxicity LD50 intraperitoneal in mouse: 3mg/kg

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