A8352712
Vincristine sulfate salt , 98% , 2068-78-2
Synonym(s):
22-Oxovincaleukoblastine sulfate salt;Leurocristine sulfate salt;V5 Tag Peptide;VCR;Vincristine sulfate salt
CAS NO.:2068-78-2
Empirical Formula: C46H58N4O14S
Molecular Weight: 923.04
MDL number: MFCD08706469
EINECS: 218-190-0
Pack Size | Price | Stock | Quantity |
25MG | RMB323.20 | In Stock |
|
100MG | RMB852.00 | In Stock |
|
500mg | RMB2773.60 | In Stock |
|
1g | RMB4991.20 | In Stock |
|
5g | RMB22399.20 | In Stock |
|
others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
Melting point: | 300 °C |
Boiling point: | 273-281 °C |
alpha | D26 +8.5° (c = 0.8) |
storage temp. | Sealed in dry,Store in freezer, under -20°C |
solubility | methanol: soluble20mg/mL |
form | lyophilized powder |
color | white to off-white |
Water Solubility | >=1 g/100 mL at 24 ºC |
BRN | 3924631 |
Stability: | Stable for 2 years from date of purchase as supplied. Solutions in distilled water may be stored at -20° for up to 3 months. |
InChIKey | AQTQHPDCURKLKT-HSMPTBRCNA-N |
IARC | 3 (Vol. 26, Sup 7) 1987 |
EPA Substance Registry System | Vincristine sulfate (2068-78-2) |
Description and Uses
Vincristine sulfate (2068-78-2) arrests cell cycle at G2/M by interfering with mitotic spindle formation. Depolymerizes microtubules and blocks binding of tubulin to microtubule proteins.1,2?Induces apoptosis.3?Vincristine sulfate is a clinically useful cancer chemotherapeutic agent.
Vincristine sulfate, is used as an anticancer agent, microtubule disrupter, Induces apoptosis in human lymphoma cells. Other applications include as a cell cycle arresting, apoptotic inducing alkaloid.
Safety
Symbol(GHS) | GHS06,GHS08 |
Signal word | Danger |
Hazard statements | H300-H341-H361fd |
Precautionary statements | P202-P264-P270-P280-P301+P310-P405 |
Hazard Codes | T |
Risk Statements | 61-36/37/38-63-23/24/25-68-62-25 |
Safety Statements | 22-24/25-53-45-37/39-26-36/37/39-36/37 |
RIDADR | UN 2811 6.1/PG 2 |
WGK Germany | 3 |
RTECS | OH6340000 |
F | 8-10 |
HazardClass | 6.1(a) |
PackingGroup | II |
HS Code | 29399990 |
Toxicity | LD50 intraperitoneal in mouse: 3mg/kg |