Norgestrel , 10mMinDMSO , 6533-00-2

Synonym(s):
Levonorgestrel;(±)-Norgestrel;(17α)-(±)-13-Ethyl-17-hydroxy-18,19-dinorpregn-4-en-20-yn-3-one;13β-Ethyl-17α-ethynyl-17β-hydroxygon-4-en-3-one;17α-Ethynyl-18-homo-19-nor-testosterone

CAS NO.：6533-00-2

Empirical Formula: C21H28O2

Molecular Weight: 312.45

MDL number: MFCD01546387

EINECS: 229-433-5

PRODUCT Properties

• Melting point: 239-241 °C(lit.)
• Boiling point: 392.36°C (rough estimate)
• Density: 1.0697 (rough estimate)
• refractive index: 1.4900 (estimate)
• storage temp.: 2-8°C
• solubility: Chloroform (Slightly, Sonicated), Dichloromethane (Slightly), Methanol (Slightly)
• form: Solid
• pka: 13.09±0.40(Predicted)
• color: Crystals from diethyl ether-hexane
• InChIKey: WWYNJERNGUHSAO-XUDSTZEESA-N

Description and Uses

Norgestrel is a synthetic progestin and a racemic mixture of dextronorgestrel and levonorgestrel , of which levonorgestrel is the biologically active component. In vivo, norgestrel administered via intrauterine device (IUD) prevents pregnancy in rats. Formulations containing nogestrel have been used as contraceptives.

It is an excellent progestational and ovulation inhibiting steroid. The bioactive enantiomer is levorotatory. Progestogen; oral contraceptive.

Safety

• Symbol(GHS): GHS07,GHS08
• Signal word: Danger
• Hazard statements: H315-H319-H360FD
• Precautionary statements: P202-P264-P280-P302+P352-P305+P351+P338-P308+P313
• Hazard Codes: Xn
• Risk Statements: 20/21/22-40
• Safety Statements: 22-36
• WGK Germany: 3
• RTECS: JF8259000
• HS Code: 2937230000
• Toxicity: LD50 oral in rat: 5010mg/kg