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A4011312

Ethisterone , ≥98% , 434-03-7

Synonym(s):
17α-Ethynyltestosterone;17β-Hydroxy-4,17α-pregnen-20-yn-3-one;4,17α-Pregnen-17β-ol-20-yn-3-one

CAS NO.:434-03-7

Empirical Formula: C21H28O2

Molecular Weight: 312.45

MDL number: MFCD00003656

EINECS: 207-096-5

Pack Size Price Stock Quantity
1G RMB31.20 In Stock
5G RMB111.20 In Stock
25G RMB288.80 In Stock
100G RMB888.00 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 263-269 °C (lit.)
Boiling point: 392.36°C (rough estimate)
alpha  D23 +23.8° (dioxane); D25 -32.0° (pyridine)
Density  1.0697 (rough estimate)
refractive index  33 ° (C=1, Pyridine)
storage temp.  room temp
solubility  Soluble to 0.05 mg/mL (0.16 mM) in DMSO
pka 13.10±0.60(Predicted)
form  Solid
color  Light yellow to yellow
Water Solubility  soluble in chloroform, DMSO (0.05 mg/ml), acetone (slightly ), ethanol (<1 mg/ml at 25°C), and water (<1 mg/ml at 25°C).
Merck  14,3741
BRN  1889895
InChIKey CHNXZKVNWQUJIB-CEGNMAFCSA-N

Description and Uses

Ethisterone is an orally bioavailable synthetic progestin and a derivative of testosterone (Item Nos. ISO60154 | 15645) that binds to progesterone and androgen receptors (EC50s = 23 and 23.1 nM, respectively, in yeast). Ethisterone (1 μM) downregulates progesterone receptors in MCF-7 cells.

Synthetic progestogen; metabolite of Danazol; intermediate in the synthesis of Spironolactone

Safety

Symbol(GHS) 
GHS08,GHS09
Signal word  Danger
Hazard statements  H360FD-H410
Precautionary statements  P201-P202-P273-P280-P308+P313-P391
Hazard Codes  Xn,T
Risk Statements  40-48-61
Safety Statements  22-24/25-45-53
RIDADR  UN 2811
WGK Germany  3
RTECS  TU5570250
HS Code  29372390

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