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A3161112

trans-Dehydroandrosterone , 99% , 53-43-0

Synonym(s):
DHEA;Dehydroepiandrosterone;Prasterone;Dehydroisoandrosterone;3β-Hydroxy-5-androsten-17-one

CAS NO.:53-43-0

Empirical Formula: C19H28O2

Molecular Weight: 288.43

MDL number: MFCD00003613

EINECS: 200-175-5

Pack Size Price Stock Quantity
1G RMB28.00 In Stock
5G RMB71.20 In Stock
25G RMB234.40 In Stock
100G RMB636.80 In Stock
500g RMB2679.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 149-151 °C(lit.)
alpha  12 º (c=2, ethanol 96% 25 ºC)
Boiling point: 370.65°C (rough estimate)
Density  1.0484 (rough estimate)
refractive index  1.4709 (estimate)
Flash point: 9℃
storage temp.  Hormones
solubility  insoluble in H2O; ≥13.7 mg/mL in DMSO; ≥58.6 mg/mL in ETOH
form  Fine Crystalline Powder
pka 15.02±0.60(Predicted)
color  White
optical activity +10.918 (c 1, ethanol)
Water Solubility  21.8mg/L(23.5 ºC)
Merck  2871
BRN  2058110
InChIKey FMGSKLZLMKYGDP-USOAJAOKSA-N
LogP 3.230

Description and Uses

Dehydroepiandrosterone(DHEA) is an endogenous steroid hormone that is secreted primarily by the adrenal gland and is the most abundant sex steroid. It is a neurohormone; small quantities of DHEA are produced in the brain and declines in serum and CSF with age. (Knopman and Henderson, 2003). Metabolites of DHEA include androstenedione , which subsequently may be metabolized to testosterone or estrone which is an estradiol precursor. In addition to serving as an intermediate in the biosynthesis of sex steroids, DHEA directly modulates a number of cellular and nuclear receptors.

Dehydroepiandrosterone (DHEA) is a major C19 steroid produced by the adrenal cortex. It is a major secretory steroidal product of the adrenal gland; secretion progresively declines with aging. May have estrogen-or androgen-like effects depending on the hormonal milieu. Intracellularly converted to androstenedione. It is used in treatment of menopausal syndrome. People living with HIV may be interested in taking DHEA for a variety of reasons, including treatment of depression, increasing bone density, decreasing arterial plaques, improvement of immune function with HIV, increased memory, and increased muscle strength.

Safety

Symbol(GHS) 
GHS08
Signal word  Warning
Hazard statements  H361fd
Precautionary statements  P201-P202-P280-P308+P313-P405-P501
Hazard Codes  Xi,T,F
Risk Statements  36/37/38-39/23/24/25-23/24/25-11
Safety Statements  26-36-24/25-45-36/37-16-7
RIDADR  UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany  2
RTECS  BV8396000
HS Code  29372900

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