Home Categories Chemical Reagents AEBSFSolution
A1031850

AEBSFSolution , 10mg/mlinH2O , 30827-99-7

Synonym(s):
AEBSF;4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride;4-(2-Aminoethyl)benzenesulfonylfluoride, HCl, 4-(2-Aminoethyl)benzene-1-sulfonyl fluoride, HCl;4-(2-Aminoethyl)benzenesulfonylfluoride, HCl, 4-(2-Aminoethyl)benzene-1-sulfonylfluoride, HCl, AEBSF, HCl InSolution;(4-(2-aminoetyl)-benzenesulfonyl fluoride hydrochloride)

CAS NO.:30827-99-7

Empirical Formula: C8H11ClFNO2S

Molecular Weight: 239.69

MDL number: MFCD00132962

EINECS: 608-547-2

Pack Size Price Stock Quantity
0.5ml RMB271.20 In Stock
2×0.5ml RMB423.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 175-177 °C
storage temp.  2-8°C
solubility  H2O: soluble50mg/mL (stable for up to six months if stored refrigerated at a pH of less than 7. If a pH of greater than 7 is required, pH adjustment should be made just prior to use.)
form  Powder
color  White
PH pH3.0~5.0 (10g/L, 25℃)
Water Solubility  10 g/L (20 ºC)
Sensitive  Moisture Sensitive
BRN  7604627
Stability: Stable for 1 year from date of purchase as supplied. Solutions at pH <7 are stable for up to 6 months if stored in the refrigerator
InChIKey WRDABNWSWOHGMS-UHFFFAOYSA-N

Description and Uses

AEBSF is a water soluble, irreversible, broad spectrum inhibitor of serine proteases, including trypsin, chymotrypsin, plasmin, thrombin, and kallikreins. AEBSF can also prevent the activation of the ROS generator, NADPH oxidase. At 10-50 μg, AEBSF can attenuate airway inflammation in a mouse model of airway allergy. AEBSF maintains stability in slightly acidic aqueous solutions and serves as a nontoxic alternative to the organophosphate inhibitors, PMSF and DFP.

Recommended concentrations for use are 0.1-1 mM.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313
Hazard Codes  C,Xi
Risk Statements  34-36/37/38
Safety Statements  45-36/37/39-26-36
RIDADR  UN 3261
WGK Germany  3
Hazard Note  Corrosive
HazardClass  8
PackingGroup  II
HS Code  29214990

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