A1031850
AEBSFSolution , 10mg/mlinH2O , 30827-99-7
Synonym(s):
AEBSF;4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride;4-(2-Aminoethyl)benzenesulfonylfluoride, HCl, 4-(2-Aminoethyl)benzene-1-sulfonyl fluoride, HCl;4-(2-Aminoethyl)benzenesulfonylfluoride, HCl, 4-(2-Aminoethyl)benzene-1-sulfonylfluoride, HCl, AEBSF, HCl InSolution;(4-(2-aminoetyl)-benzenesulfonyl fluoride hydrochloride)
CAS NO.:30827-99-7
Empirical Formula: C8H11ClFNO2S
Molecular Weight: 239.69
MDL number: MFCD00132962
EINECS: 608-547-2
Pack Size | Price | Stock | Quantity |
0.5ml | RMB271.20 | In Stock |
|
2×0.5ml | RMB423.20 | In Stock |
|
others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
Melting point: | 175-177 °C |
storage temp. | 2-8°C |
solubility | H2O: soluble50mg/mL (stable for up to six months if stored refrigerated at a pH of less than 7. If a pH of greater than 7 is required, pH adjustment should be made just prior to use.) |
form | Powder |
color | White |
PH | pH3.0~5.0 (10g/L, 25℃) |
Water Solubility | 10 g/L (20 ºC) |
Sensitive | Moisture Sensitive |
BRN | 7604627 |
Stability: | Stable for 1 year from date of purchase as supplied. Solutions at pH <7 are stable for up to 6 months if stored in the refrigerator |
InChIKey | WRDABNWSWOHGMS-UHFFFAOYSA-N |
Description and Uses
AEBSF is a water soluble, irreversible, broad spectrum inhibitor of serine proteases, including trypsin, chymotrypsin, plasmin, thrombin, and kallikreins. AEBSF can also prevent the activation of the ROS generator, NADPH oxidase. At 10-50 μg, AEBSF can attenuate airway inflammation in a mouse model of airway allergy. AEBSF maintains stability in slightly acidic aqueous solutions and serves as a nontoxic alternative to the organophosphate inhibitors, PMSF and DFP.
Recommended concentrations for use are 0.1-1 mM.
Safety
Symbol(GHS) | GHS07 |
Signal word | Warning |
Hazard statements | H315-H319 |
Precautionary statements | P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313 |
Hazard Codes | C,Xi |
Risk Statements | 34-36/37/38 |
Safety Statements | 45-36/37/39-26-36 |
RIDADR | UN 3261 |
WGK Germany | 3 |
Hazard Note | Corrosive |
HazardClass | 8 |
PackingGroup | II |
HS Code | 29214990 |