Home Categories Biochemical Engineering Leupeptin hemisulfate salt
A5268212

Leupeptin hemisulfate salt , ≥90%(HPLC) , 103476-89-7

Synonym(s):
Leupeptin hemisulfate;Leupeptin hemisulfate salt;N-Acetyl-L-leucyl-L-leucyl-L-argininal hemisulfate salt;N-Acetyl-L-leucyl-L-leucyl-L-argininal;Acetyl-L-leucyl-L-leucylargininal

CAS NO.:103476-89-7

Empirical Formula: C20H38N6O4

Molecular Weight: 426.55

MDL number: MFCD00081028

EINECS: 600-443-5

Pack Size Price Stock Quantity
1mg RMB159.20 In Stock
5MG RMB239.20 In Stock
25MG RMB858.40 In Stock
100MG RMB3020.80 In Stock
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Update time: 2022-07-08

PRODUCT Properties

alpha  -76 º (c=1, water)
storage temp.  -20°C
solubility  H2O: 10 mM Solutions are stable for a week at 4 °C. Stock solutions are stable up to 6 months at −20°C.
form  Powder
color  White to Off-white
Water Solubility  soluble
Stability: Stable for 1 year from date of purchase as supplied Solutions in distilled water, ethanol or methanol may be stored at -20°C for up to 3 months.
InChIKey CIPMKIHUGVGQTG-VFFZMTJFSA-N

Description and Uses

Leupeptin hemisulfate (103476-89-7) is a reversible inhibitor of trypsin-like proteases and cysteine proteases. Inhibits trypsin, plasmin, papain and cathepsin B, H and L.1-3?Blocks various apoptotic pathways in T cells.4?Commonly used in cell lysis buffers to protect proteins from degradation. Typical working concentration is 1μM (0.5 μg/ml).

Leupeptin has been used as a protease inhibitor: in ice-cold lysis buffer to harvest cells for western immunoblotting and immunoprecipitation,in chromatin immunoprecipitation (ChIP) lysis buffer for the isolation of fragmented chromatin samples in lysis buffer I to lyse the cells for tandem affinity purification (TAP)

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302+H312+H332
Precautionary statements  P261-P264-P280-P302+P352+P312-P304+P340+P312-P501
Hazard Codes  Xn
Risk Statements  20/21/22-63-36/37/38
Safety Statements  22-24/25-36/37-36-36/37/39-26-7/8
RIDADR  3077
WGK Germany  3
10-23
HS Code  29252900

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