Vilazodone Hydrochloride , >98.0%(HPLC) , 163521-08-2
Synonym(s):
5-[4-[4-(5-Cyano-1H-indol-3-yl)butyl]-1-piperazinyl]- 2-benzofurancarboxamide hydrochloride;EMD 68843;SB 659746A.
CAS NO.：163521-08-2
Empirical Formula: C26H28ClN5O2
Molecular Weight: 477.986
MDL number: MFCD00940014
EINECS: 695-883-8
| Pack Size | Price | Stock | Quantity |
| 50mg | RMB348.00 | In Stock |
|
| 200mg | RMB764.00 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 279°C(lit.) |
| Flash point: | 9℃ |
| storage temp. | Inert atmosphere,Store in freezer, under -20°C |
| solubility | DMSO: soluble20mg/mL, clear |
| form | powder |
| color | white to beige |
| Stability: | Hygroscopic |
Description and Uses
Vilazodone is a selective serotonin reuptake inhibitor (SSRI) and a partial agonist of the serotonin (5-HT) receptor subtype 5-HT1A (IC50s = 0.2 and 0.5 nM, respectively). It increases extracellular 5-HT in the rat ventral hippocampus and frontal cortex when administered intraperitoneally at doses of 1 and 3 mg/kg. Vilazodone (1 mg/kg, i.p.) decreases immobility in the forced swim test in both rats and mice. Formulations containing vilazodone have been used in the treatment of depression.
Vilazodone Hydrochloride, is the salt form of Vilazodone (V265000), which is a combined serotonin specific reuptake inhibitor (SSRI) and 5-HT1A receptor partial agonist currently under clinical evaluation for the treatment of major depression. Antidepressant.
Safety
| Symbol(GHS) |  GHS08 |
| Signal word | Warning |
| Hazard statements | H361d |
| Precautionary statements | P201-P202-P280-P308+P313-P405-P501 |
| Hazard Codes | F,T |
| Risk Statements | 11-23/24/25-39/23/24/25 |
| Safety Statements | 7-16-36/37-45 |
| RIDADR | UN1230 - class 3 - PG 2 - Methanol, solution |
| WGK Germany | 3 |
| HS Code | 29329990 |
