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M5971635

Terlipressin , >99% , 14636-12-5

CAS NO.:14636-12-5

Empirical Formula: C52H74N16O15S2

Molecular Weight: 1227.37

MDL number: MFCD00155450

EINECS: 238-680-8

Pack Size Price Stock Quantity
10mg RMB850.40 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: >170°C (dec.)
Boiling point: 1824.0±65.0 °C(Predicted)
Density  1.46±0.1 g/cm3(Predicted)
storage temp.  Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility  DMSO (Slightly), Methanol (Slightly)
form  Solid
pka 9.90±0.15(Predicted)
color  White
Sequence Gly-Gly-Gly-c[Cys-Tyr-Phe-Gln-Asn-Cys]-Pro-Lys-Gly-NH2,(Disulfide bridge: Cys-Cys)
InChIKey BENFXAYNYRLAIU-ITQMCZIINA-N
CAS DataBase Reference 14636-12-5(CAS DataBase Reference)

Description and Uses

Terlipressin acetate is a novel synthetic long-acting vasopressin preparation. It is a kind of prodrug, which is inactive by itself. After the action of aminopeptidase in the body, after removing the three glycyl residues at its N-terminus, it slowly "releases" the active lysine vasopressin. Therefore, terlipressin acts as a reservoir that releases lysine vasopressin at a steady rate.

Terlipressin is an analogue of vasopressin used as a vasoactive drug in the management of hypotension. It is used norepinephrine-resistant septic shock and hepatorenal syndrome. It is also used in the treatment of acute variceal bleeding. Terlipressin Acetate 1 mg solution for injection is used for the treatment of: bleeding from dilated (widening) veins in the food pipe leading to your stomach (called bleeding oesophageal varices).

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H332
Precautionary statements  P261-P271-P304+P340-P312
HS Code  3504009000

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