Adrenocorticotropic Hormone Fragment 1-24 human , ≥97%(HPLC), 0-13%of acetic acid , 16960-16-0

Synonym(s):
α^1-24-Corticotropin acetate salt;Tetracosactide;Tetracosactide acetate salt;Tetracosactrin acetate salt

CAS NO.：16960-16-0

Empirical Formula: C136H210N40O31S

Molecular Weight: 2933.44

MDL number: MFCD00167476

EINECS: 241-031-1

PRODUCT Properties

• Density: 1.47±0.1 g/cm3(Predicted)
• storage temp.: −20°C
• solubility: Sparingly soluble in water.
• form: Solid
• color: White to off-white
• Water Solubility: Soluble in water
• Sequence: H-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-Gly-Lys-Lys-Arg-Arg-Pro-Val-Lys-Val-Tyr-Pro-OH
• Stability: Hygroscopic
• InChIKey: ZOEFCCMDUURGSE-SQKVDDBVSA-N

Description and Uses

Cosyntropin (Tetracosactide acetate) is a synthetic polypeptide that consists of amino acid residues 1 through 24 of human ACTH, but that has the full biological activity of its parent. Because it is of synthetic origin, it is less allergenic than ACTH of natural origin. Cosyntropin is used as a diagnostic agent in the screening of patients suspected of having adrenocortical insufficiency. Normally, parenteral administration of cosyntropin acts rapidly on the adrenal cortex to effect release of plasma hydrocortisone; when performing the test, the hydrocortisone levels are compared to a control blood sample taken earlier.

Adrenocorticotropic Hormone Fragment 1-24 human, rat, has been used in corticosterone enzyme immunoassay and to induce color change in frogs.

Safety

• Symbol(GHS): GHS07,GHS08
• Signal word: Danger
• Hazard statements: H332-H317-H334
• Precautionary statements: P261-P271-P304+P340-P312-P261-P285-P304+P341-P342+P311-P501-P261-P272-P280-P302+P352-P333+P313-P321-P363-P501
• WGK Germany: 3
• RTECS: GM7915000
• HS Code: 2937220000