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M4028635

Mezlocillinsodium , 96% , 59798-30-0

CAS NO.:59798-30-0

Empirical Formula: C22H27N6NaO9S2

Molecular Weight: 606.6

MDL number: MFCD07793332

Pack Size Price Stock Quantity
200mg RMB52.80 In Stock
1g RMB84.80 In Stock
5g RMB249.60 In Stock
25g RMB832.00 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 197-201°C (dec.)
storage temp.  Refrigerator
solubility  DMSO (Slightly), Methanol (Slightly)
form  Solid
color  White to Off-White
Water Solubility  Soluble in water or DMSO
CAS DataBase Reference 59798-30-0(CAS DataBase Reference)

Description and Uses

Mezlocillin is a β-lactam antibiotic and derivative of ampicillin . It is active against B. fragilis, E. lentum, P. morbillorum, and F. nucleatum (MICs = 8, 4, 2, and 4 μg/ml, respectively). Mezlocillin (32 μg/ml) is also active against 10 strains of S. faecalis. In vivo, mezlocillin (240 mg/kg) increases survival and reduces bacteremia in a rabbit model of S. faecalis endocarditis. It completely eliminates lung P. morbillorum, E. lentum, and F. nucelatum, but not B. fragilis, in a rabbit model of pulmonary P. morbillorum, E. lentum, F. nucelatum, and B. fragilis infection when administered at a dose of 300 mg/kg. Formulations containing mezlocillin have been used in the treatment of various bacterial infections.

Antibacterial.

Safety

Symbol(GHS) 
GHS08
Signal word  Danger
Hazard statements  H334
Precautionary statements  P261-P285-P304+P341-P342+P311-P501

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