Mezlocillinsodium , 96% , 59798-30-0
CAS NO.:59798-30-0
Empirical Formula: C22H27N6NaO9S2
Molecular Weight: 606.6
MDL number: MFCD07793332
Pack Size | Price | Stock | Quantity |
200mg | RMB52.80 | In Stock |
|
1g | RMB84.80 | In Stock |
|
5g | RMB249.60 | In Stock |
|
25g | RMB832.00 | In Stock |
|
others | Enquire |
PRODUCT Properties
Melting point: | 197-201°C (dec.) |
storage temp. | Refrigerator |
solubility | DMSO (Slightly), Methanol (Slightly) |
form | Solid |
color | White to Off-White |
Water Solubility | Soluble in water or DMSO |
Description and Uses
Mezlocillin is a β-lactam antibiotic and derivative of ampicillin . It is active against B. fragilis, E. lentum, P. morbillorum, and F. nucleatum (MICs = 8, 4, 2, and 4 μg/ml, respectively). Mezlocillin (32 μg/ml) is also active against 10 strains of S. faecalis. In vivo, mezlocillin (240 mg/kg) increases survival and reduces bacteremia in a rabbit model of S. faecalis endocarditis. It completely eliminates lung P. morbillorum, E. lentum, and F. nucelatum, but not B. fragilis, in a rabbit model of pulmonary P. morbillorum, E. lentum, F. nucelatum, and B. fragilis infection when administered at a dose of 300 mg/kg. Formulations containing mezlocillin have been used in the treatment of various bacterial infections.
Antibacterial.
Safety
Symbol(GHS) | GHS08 |
Signal word | Danger |
Hazard statements | H334 |
Precautionary statements | P261-P285-P304+P341-P342+P311-P501 |