LN-705514
guanethidine , 99.9% , 55-65-2
Update time: 2023-04-23
PRODUCT Properties
| Boiling point: | 325.64°C (rough estimate) |
| Density | 0.9402 (rough estimate) |
| refractive index | 1.4910 (estimate) |
| storage temp. | Store at -20°C |
| pka | pKa 11.4 (Uncertain) |
Description and Uses
Guanethidine is used for severe hypertension when the use of the more generally
accepted drugs turns out to be unsuccessful. It is a powerful, long-lasting antihypertensive
drug; however, it affects a patient’s blood pressure only in the orthostatic position, and not
when lying down.
Guanethidine is a very powerful and long-lasting drug, and its action often lasts 2–3
days after its use has been stopped.
Antihypertensive.
Safety
| Toxicity | LD50 oral in rat: 1050mg/kg |
