GuanethidineMonosulfate , 98% , 645-43-2
Synonym(s):
1-(2-Guanidinoethyl)octahydroazocine;Guanethidine monosulfate (1:1)
CAS NO.：645-43-2
Empirical Formula: C10H24N4O4S
Molecular Weight: 296.39
MDL number: MFCD00035403
EINECS: 211-442-0
| Pack Size | Price | Stock | Quantity |
| 250mg | RMB309.60 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 276-281 °C |
| storage temp. | 2-8°C |
| solubility | Freely soluble in water, practically insoluble in ethanol (96 per cent) |
| form | Solid |
| color | White to Off-White |
| Stability: | Hygroscopic |
| InChIKey | YUFWAVFNITUSHI-UHFFFAOYSA-N |
Description and Uses
Guanethidine is an antihypertensive compound that competes with norepinephrine for transport into presynaptic terminals of adrenergic neurons by the norepinephrine transporter. Once guanethidine has entered the nerve, it becomes concentrated in synaptic vesicles, depleting endogenous norepinephrine, and thus, reducing the release of norepinephrine in response to action potentials. Guanethidine’s actions are restricted to peripheral nerve terminals because its basic guanidine group does not allow passage through the blood brain barrier. Its use has been explored in the relief of chronic pain caused by complex regional pain syndrome.
Guanethidine Monosulfate acts as an antihypertensive; antiglaucoma
