LN-657520
7-AMINO-3-BETA-D-RIBOFURANOSYL-1H-PYRAZOLO[4,3-D]PYRIMIDINE MONOHYDRATE , 97% , 6742-12-7
Synonym(s):
1-C-(7-Amino-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-1,4-anhydro-(1S)-D-Ribitol;7-Amino-3-(β-D -ribofuranosyl)-1H-pyrazolo[4,3-d]pyrimidine;8-Aza-9-deazaadenosine;Formycin;NSC 102811
Update time: 2023-04-23
PRODUCT Properties
Melting point: | 141-144 °C (decomp) |
Boiling point: | 709.5±60.0 °C(Predicted) |
Density | 1.771±0.06 g/cm3(Predicted) |
storage temp. | −20°C |
solubility | DMSO: soluble1mg/mL |
form | powder |
pka | 8.37±0.50(Predicted) |
color | white to off-white |
BRN | 624229 |
Description and Uses
Formycin (Formycin A) is isolated from Nocardia interforma and from Streptomyces lavendulae , . The antibiotic is effective against Xanthomonas oryzae and Pellicularia filamentosa. Its activity against Yoshida rat sarcoma cell is enhanced by coformycin. Formycin B inhibits Xanthomonas oryzae and interferes with multiplication of influenza A virus in the cells of chick chorioallantoic membrane . Oxoformycin B shows no activity against Xanthomonas oryzae .