PRODUCT Properties
Melting point: | 102-108° |
alpha | D25 +146° |
pka | pKa 8.2(66% DMF) (Uncertain);7.9(H2O) (Uncertain) |
CAS DataBase Reference | 1403-66-3(CAS DataBase Reference) |
EPA Substance Registry System | Gentamicin (1403-66-3) |
Description and Uses
Gentamicin is a mixture of several antibiotic components produced by fermentation of Mi cromonospora purpurea and other related soil microorganisms (hence its name is spelled with an “i” instead of a “ y”). Gentamicins C-1, C-2, and C-1a are most prominent. Gentamicin is the most important of the aminoglycoside antibiotics still in use. Gentamicin was, for example, one of the first antibiotics to have significant activity against Pseudomonas aeruginosa infections. This water-loving, opportunistic pathogen frequently is encountered in burns, pneumonias, and urinary tract infections.
antibacterial
Safety
Symbol(GHS) | GHS08 |
Signal word | Danger |
Hazard statements | H317-H334 |
Precautionary statements | P261-P285-P304+P341-P342+P311-P501-P261-P272-P280-P302+P352-P333+P313-P321-P363-P501 |
Hazardous Substances Data | 1403-66-3(Hazardous Substances Data) |