PRODUCT Properties
| Melting point: | 206-209°C (dec.) |
| Boiling point: | 554.44°C (rough estimate) |
| Density | 1.3809 (rough estimate) |
| refractive index | 1.6500 (estimate) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| solubility | DMSO : 125 mg/mL (281.26 mM; Need ultrasonic) |
| pka | pKa 3.5 (Uncertain);7.7 (Uncertain);9.5 (Uncertain) |
| form | Solid |
| color | Light yellow to brown |
| Water Solubility | 0.63g/L(25 ºC) |
| BCS Class | 3,1 |
| InChIKey | JBIWCJUYHHGXTC-AKNGSSGZSA-N |
| SMILES | C1(=O)[C@]2(O)[C@@]([H])([C@@H](O)[C@@]3([H])C(=C2O)C(=O)C2=C(C=CC=C2O)[C@@H]3C)[C@H](N(C)C)C(O)=C1C(N)=O |
Description and Uses
Doxycycline is used for the same indications as other antibiotics of the tetracycline series; however, it belongs to the group of long-lasting tetracyclines. In some cases it is more active with respect to a number of organisms, and is better tolerated than other tetracyclines. Synonyms of this drug are azudoxat, codidoxal, eftapan, vibramycin, and others.
