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A1317950

Oxytetracycline , ≥98% , 79-57-2

Synonym(s):
OTC;Oxytetracycline dihydrate

CAS NO.:79-57-2

Empirical Formula: C22H24N2O9

Molecular Weight: 460.43

MDL number: MFCD00003700

EINECS: 201-212-8

Pack Size Price Stock Quantity
25g RMB32.00 In Stock
100g RMB105.60 In Stock
500g RMB376.00 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 183 °C
alpha  -223 º (c=1 0.03N HCl)
Boiling point: 565.29°C (rough estimate)
Density  1.6340
refractive index  1.6500 (estimate)
storage temp.  Keep in dark place,Inert atmosphere,Room temperature
solubility  Sparingly soluble in aqueous solution at 0.6 mg/mL
pka pKa 3.27/7.32/9.11(H2O,t =25,I<0.01)(Approximate)
form  Crystalline Powder
color  Beige to light yellow
Water Solubility  0.2 g/L
InChIKey IWVCMVBTMGNXQD-PXOLEDIWSA-N
LogP -0.900
CAS DataBase Reference 79-57-2(CAS DataBase Reference)
EPA Substance Registry System Oxytetracycline (79-57-2)

Description and Uses

Oxytetracycline also is one of the classic tetracyclines. It is produced by fermentation of Streptomyces rimosis and other soil microorganisms. The most hydrophilic tetracycline on the market, it has largely now been replaced by its semisynthetic descendants. It is primarily used today for IM injections.

Oxytetracycline, which has seen significant usage in plant disease control, does not contain the Cl atom but has an additional -OH group at the C5 position on the tetracycline molecule (4). Tetracyclines are widely used therapeutic agents in clinical medicine [second to penicillins in total tons used each year (5)] for bacterial respiratory, periodontal, and urogenital tract diseases (6). Oxytetracycline is also used as a feed amendment for growth promotion and as a therapeutic agent for curing diseases of agricultural animals including fish.

Safety

Symbol(GHS) 
GHS08,GHS09
Signal word  Warning
Hazard statements  H361d-H411
Precautionary statements  P201-P202-P273-P280-P308+P313-P391
Hazard Codes  Xn,Xi
Risk Statements  63-36-36/37/38
Safety Statements  22-24/25-36/37/39-26-36
WGK Germany  2
RTECS  QI7875000
TSCA  Yes
HS Code  30029090
Hazardous Substances Data 79-57-2(Hazardous Substances Data)
Toxicity LD50 oral in rat: 4800mg/kg

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