Oxytetracycline , ≥98% , 79-57-2

Synonym(s):
OTC;Oxytetracycline dihydrate

CAS NO.：79-57-2

Empirical Formula: C22H24N2O9

Molecular Weight: 460.43

MDL number: MFCD00003700

EINECS: 201-212-8

PRODUCT Properties

• Melting point: 183 °C
• alpha: -223 º (c=1 0.03N HCl)
• Boiling point: 565.29°C (rough estimate)
• Density: 1.6340
• refractive index: 1.6500 (estimate)
• storage temp.: Keep in dark place,Inert atmosphere,Room temperature
• solubility: Sparingly soluble in aqueous solution at 0.6 mg/mL
• form: Crystalline Powder
• pka: pKa 3.27/7.32/9.11(H2O,t =25,I<0.01)(Approximate)
• color: Beige to light yellow
• Water Solubility: 0.2 g/L
• InChIKey: IWVCMVBTMGNXQD-PXOLEDIWSA-N
• LogP: -0.900

Description and Uses

Oxytetracycline also is one of the classic tetracyclines. It is produced by fermentation of Streptomyces rimosis and other soil microorganisms. The most hydrophilic tetracycline on the market, it has largely now been replaced by its semisynthetic descendants. It is primarily used today for IM injections.

Oxytetracycline, which has seen significant usage in plant disease control, does not contain the Cl atom but has an additional -OH group at the C5 position on the tetracycline molecule (4). Tetracyclines are widely used therapeutic agents in clinical medicine [second to penicillins in total tons used each year (5)] for bacterial respiratory, periodontal, and urogenital tract diseases (6). Oxytetracycline is also used as a feed amendment for growth promotion and as a therapeutic agent for curing diseases of agricultural animals including fish.

Safety

• Symbol(GHS): GHS08,GHS09
• Signal word: Warning
• Hazard statements: H361d-H411
• Precautionary statements: P201-P202-P273-P280-P308+P313-P391
• Hazard Codes: Xn,Xi
• Risk Statements: 63-36-36/37/38
• Safety Statements: 22-24/25-36/37/39-26-36
• WGK Germany: 2
• RTECS: QI7875000
• TSCA: Yes
• HS Code: 30029090
• Toxicity: LD50 oral in rat: 4800mg/kg