LN-515792
(1S,3S,7S,10R,11S,12S,16R)-3-[(1E)-2-[2-(Aminomethyl)-4-thiazolyl]-1-methylethenyl]-7,11-dihydroxy-8,8,10,12,16-pentamethyl-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione , 99.0% , 280578-49-6
Update time: 2023-04-23
PRODUCT Properties
Boiling point: | 703.1±60.0 °C(Predicted) |
Density | 1.160 |
form | Solid |
pka | 13.57±0.70(Predicted) |
color | Off-white to light yellow |
Description and Uses
BMS 310705 (21-Aminoepothilone B) is an analog of Epothilone B (HY-17029), targeting to malignancies such as ovarian, renal, bladder, and lung carcinoma. BMS 310705 induces significant apoptosis via mitochondrial-mediated pathway[1].