5'-O-[Bis(4-Methoxyphenyl)phenylmethyl]-thymidine 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] , 97% , 98796-51-1

Synonym(s):
5′-O-(4,4′-dimethoxytrityl)-2′-deoxythymidine-3′-O-[O-(2-cyanoethyl)-N,N′-diisopropylphosphoramidite];5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxythymidine, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite];DMT-dT amidite;DMT-dT Phosphoramidite;Thymidine, 5′-O-[bis(4-methoxyphenyl)phenylmethyl]-, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]

CAS NO.：98796-51-1

Empirical Formula: C40H49N4O8P

Molecular Weight: 744.81

MDL number: MFCD00055063

EINECS: 685-410-3

PRODUCT Properties

• Density: 1.22 at 20℃
• vapor pressure: 0-0Pa at 20-50℃
• storage temp.: Sealed in dry,2-8°C
• solubility: soluble, clear
• form: powder or granules
• pka: 9.55±0.10(Predicted)
• color: white to off-white
• InChIKey: UNOTXUFIWPRZJX-DJKSPSSYNA-N
• SMILES: O(C(C1=CC=C(OC)C=C1)(C1=CC=C(OC)C=C1)C1=CC=CC=C1)C[C@H]1O[C@@H](N2C=C(C)C(=O)NC2=O)C[C@@H]1OP(N(C(C)C)C(C)C)OCCC#N |&1:25,27,38,r|
• LogP: 5.8 at 20℃

Description and Uses

5''-O-[Bis(4-Methoxyphenyl)phenylmethyl]-thymidine 3''-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] is a nucleotide and reactant used in the solid-phase synthesis of phosphorothioate oligonucleotides, and in the synthesis of lipophilic 5''-phosphoramidate derivatives of DNA and RNA oligonucleotides.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H319
• Precautionary statements: P264-P280-P305+P351+P338-P337+P313P
• WGK Germany: 3
• HS Code: 29349990