Home Categories Organic Chemistry N,N-Diisopropylethylamine
A3189812

N,N-Diisopropylethylamine , 99% , 7087-68-5

Synonym(s):
DIPEA;N,N-Diisopropylethylamine;Ethyldiisopropylamine;N-Ethyldiisopropylamine;Hünig’s base

CAS NO.:7087-68-5

Empirical Formula: C8H19N

Molecular Weight: 129.24

MDL number: MFCD00008868

EINECS: 230-392-0

Update time: 2022-07-08

PRODUCT Properties

Melting point: <-50 °C (lit.)
Boiling point: 127 °C (lit.)
Density  0.742 g/mL at 25 °C (lit.)
vapor pressure  31 mmHg ( 37.7 °C)
refractive index  n20/D 1.457
Flash point: 6 °C
storage temp.  Store below +30°C.
solubility  miscible
form  Liquid
pka 10.98±0.28(Predicted)
color  APHA: <20
Specific Gravity 0.755 (20/4℃)
PH 12.3 (H2O, 20℃)(as an emulsion)
explosive limit 0.7-6.3%(V)
Water Solubility  miscible
BRN  605301
Stability: Volatile
InChIKey JGFZNNIVVJXRND-UHFFFAOYSA-N
LogP -1.8 at 22.5℃

Description and Uses

N,N-Diisopropylethylamine is used as a base in organic reactions. Used in the preparation of (-)Gambierol a marine polycyclic ether toxin. It is also used in the synthesis of potent inhibitors of human brain memapsin, a key effector in the progression of Alzheimer’s disease.

Safety

Symbol(GHS) 
GHS02,GHS05,GHS06,GHS09
Signal word  Danger
Hazard statements  H225-H302-H318-H331-H335-H411
Precautionary statements  P210-P273-P280-P301+P312-P304+P340+P311-P305+P351+P338
Hazard Codes  C,F,T
Risk Statements  11-22-34-52/53-20/21/22-10-41-37/38-20/22-36/37/38-61
Safety Statements  26-36/37/39-45-61-16-27-60-23-9-53
RIDADR  UN 2734 8/PG 2
WGK Germany  2
9-34
Autoignition Temperature 240 °C
Hazard Note  Highly Flammable/Corrosive/Harmful
TSCA  Yes
HazardClass  3
PackingGroup  II
HS Code  29211980
Toxicity LD50 orally in Rabbit: > 200 - 500 mg/kg

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