A3189912
N,N-Diisopropylethylamine , Rehabilitation, 99.5% , 7087-68-5
Synonym(s):
DIPEA;N,N-Diisopropylethylamine;Ethyldiisopropylamine;N-Ethyldiisopropylamine;Hünig’s base
CAS NO.：7087-68-5
Empirical Formula: C8H19N
Molecular Weight: 129.24
MDL number: MFCD00008868
EINECS: 230-392-0
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | <-50 °C (lit.) |
| Boiling point: | 127 °C (lit.) |
| Density | 0.742 g/mL at 25 °C (lit.) |
| vapor pressure | 31 mmHg ( 37.7 °C) |
| refractive index | n |
| Flash point: | 6 °C |
| storage temp. | Store below +30°C. |
| solubility | miscible |
| form | Liquid |
| pka | 10.98±0.28(Predicted) |
| color | APHA: <20 |
| Specific Gravity | 0.755 (20/4℃) |
| PH | 12.3 (H2O, 20℃)(as an emulsion) |
| explosive limit | 0.7-6.3%(V) |
| Water Solubility | miscible |
| BRN | 605301 |
| Stability: | Volatile |
| InChIKey | JGFZNNIVVJXRND-UHFFFAOYSA-N |
| LogP | -1.8 at 22.5℃ |
Description and Uses
N,N-Diisopropylethylamine is used as a base in organic reactions. Used in the preparation of (-)Gambierol a marine polycyclic ether toxin. It is also used in the synthesis of potent inhibitors of human brain memapsin, a key effector in the progression of Alzheimer’s disease.
Safety
| Symbol(GHS) |     GHS02,GHS05,GHS06,GHS09 |
| Signal word | Danger |
| Hazard statements | H225-H302-H318-H331-H335-H411 |
| Precautionary statements | P210-P273-P280-P301+P312-P304+P340+P311-P305+P351+P338 |
| Hazard Codes | C,F,T |
| Risk Statements | 11-22-34-52/53-20/21/22-10-41-37/38-20/22-36/37/38-61 |
| Safety Statements | 26-36/37/39-45-61-16-27-60-23-9-53 |
| RIDADR | UN 2734 8/PG 2 |
| WGK Germany | 2 |
| F | 9-34 |
| Autoignition Temperature | 240 °C |
| Hazard Note | Highly Flammable/Corrosive/Harmful |
| TSCA | Yes |
| HazardClass | 3 |
| PackingGroup | II |
| HS Code | 29211980 |
| Toxicity | LD50 orally in Rabbit: > 200 - 500 mg/kg |
