Etofibrate , 98% , 31637-97-5

Synonym(s):
2-[(Pyridin-3-yl)carbonyloxy]ethyl 2-(4-chlorophenoxy)-2-methylpropanoate;3-Pyridinecarboxylic acid 2-[2-(4-chlorophenoxy)-2-methyl-1-oxopropoxy]ethyl ester

CAS NO.：31637-97-5

Empirical Formula: C18H18ClNO5

Molecular Weight: 363.79

MDL number: MFCD00865727

EINECS: 250-743-1

PRODUCT Properties

• Melting point: 42-44°C
• Boiling point: 486.8±35.0 °C(Predicted)
• Density: 1.2303 (rough estimate)
• refractive index: 1.6500 (estimate)
• storage temp.: Sealed in dry,2-8°C
• solubility: Chloroform (Slightly), Methanol (Slightly)
• form: Solid
• pka: 3.04±0.10(Predicted)
• color: White to Off-White
• Water Solubility: 7.276mg/L(room temperature)
• BRN: 497931

Description and Uses

Etofibrate is a combination of niacin and clofibrate that acts as a hypolipidemic agent. In vivo, etofibrate decreases plasma cholesterol and triglyceride concentrations and increases bile cholesterol content in rats. It also decreases thromboxane formation, platelet aggregation, and plasma viscosity and inhibits neointima formation in a carotid artery balloon injury rat model. Formulations containing etofibrate have been used to treat hyperlipidemia.

Antilipemic; reducing lipid levels in the blood.

Safety

• WGK Germany: 3
• HS Code: 2933.39.4100