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A7111612

Reserpine , ≥98.0%(HPLC) , 50-55-5

Synonym(s):
(3β, 16β, 17α, 18β, 20α)-11,17-Dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]yohimban-16-carboxylic acid methyl ester;Reserpine;Reserpine - CAS 50-55-5 - Calbiochem;VMAT2 Inhibitor, Reserpine, Vesicular monoamine transporter (VMAT) Antagonist, Reserpine

CAS NO.:50-55-5

Empirical Formula: C33H40N2O9

Molecular Weight: 608.69

MDL number: MFCD00005091

EINECS: 200-047-9

Pack Size Price Stock Quantity
1G RMB156.00 In Stock
5G RMB531.20 In Stock
25G RMB2639.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: ~265 °C (dec.)
alpha  D23 -118° (CHCl3); D26 -164° (c = 0.96 in pyridine); D26 -168° (c = 0.624 in DMF)
Boiling point: 655.12°C (rough estimate)
Density  1.2336 (rough estimate)
refractive index  177 ° (C=1, DMF)
Flash point: 22℃
storage temp.  Inert atmosphere,Room Temperature
solubility  Practically insoluble in water, very slightly soluble in ethanol (96 per cent).
pka 6.6(at 25℃)
form  Solid
color  Off-white
optical activity [α]20/D 123±3°, c = 1% in chloroform
Water Solubility  Soluble in water.
Merck  14,8145
BRN  102014
Stability: Stable, but darkens slowly in light. Combustible. Incompatible with strong acids, reducing agents, oxidizing agents.
InChIKey QEVHRUUCFGRFIF-MDEJGZGSSA-N
LogP 4.050 (est)
CAS DataBase Reference 50-55-5
NIST Chemistry Reference Reserpine(50-55-5)
IARC 3 (Vol. 24, Sup 7) 1987
EPA Substance Registry System Reserpine (50-55-5)

Description and Uses

Reserpine causes release of norepinephrine, dopamine, and serotonin at neuronal termini. It weakens the intracellular uptake of biogenic amines and decreases the ability to store them in vesicles.

An indole alkaloid found in Rauwolfia serpentina. Inhibits vesicular uptake of catecholamines and serotonin. Reserpine is reasonably anticipated to be a human carcinogen. Antihypertensive.

Safety

Symbol(GHS) 
GHS07,GHS08
Signal word  Danger
Hazard statements  H302-H336-H351-H360D
Precautionary statements  P201-P301+P312+P330-P308+P313
Hazard Codes  Xn,Xi
Risk Statements  22-67-36-10
Safety Statements  22-36/37/39-26
RIDADR  3077
WGK Germany  3
RTECS  ZG0350000
10-23
TSCA  Yes
PackingGroup  II
HS Code  29399990
Hazardous Substances Data 50-55-5(Hazardous Substances Data)
Toxicity LD50 oral in rat: 420mg/kg

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