Piracetam , 98% , 7491-74-9

Synonym(s):
2-(2-Oxopyrrolidino)acetamide;2-Oxo-1-pyrrolidineacetamide

CAS NO.：7491-74-9

Empirical Formula: C6H10N2O2

Molecular Weight: 142.16

MDL number: MFCD00079246

EINECS: 231-312-7

PRODUCT Properties

• Melting point: 151-152,5 C
• Boiling point: 259.72°C (rough estimate)
• Density: 1.2298 (rough estimate)
• refractive index: 1.5010 (estimate)
• storage temp.: 2-8°C
• solubility: Freely soluble in water, soluble in ethanol (96 per cent). It shows polymorphism (5.9).
• form: Solid
• pka: 15.67±0.40(Predicted)
• color: Crystals from isopropanol
• Water Solubility: Soluble in water (100mM)
• InChI: InChI=1S/C6H10N2O2/c7-5(9)4-8-3-1-2-6(8)10/h1-4H2,(H2,7,9)
• InChIKey: GMZVRMREEHBGGF-UHFFFAOYSA-N
• SMILES: N1(CC(N)=O)CCCC1=O
• CAS DataBase Reference: 7491-74-9(CAS DataBase Reference)
• NIST Chemistry Reference: Piracetam(7491-74-9)

Description and Uses

Piracetam is a nootropic agent with an indication as adjunctive treatment for myoclonus of cortical origin, as well as tardive dyskinesia. However, piracetam is not approved by the FDA for any medical use in the USA. Piracetam should not be prescribed in patients with Huntington disease, those with serious kidney problems, or patients who have experienced a brain haemorrhage. Bleeding problems are a further caution to be taken into account. Although there is little evidence for piracetam’s efficacy in terms of long- term benefits for the treatment of mild cognitive impairments, recent studies showed that it is effective in the treatment of cognitive disorders of cerebrovascular and traumatic origins. With regard to piracetam’s behavioural profile, its beneficial effects on lowering depression and anxiety appear to be higher than its positive effects on memory.

Piracetam has been used to study crystal structure and physicochemical properties of six co-crystals of piracetam. It has also been used to study its in vitro antioxidant properties.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302
• Precautionary statements: P264-P270-P301+P312-P330-P501
• Hazard Codes: Xi
• Risk Statements: 36/37/38
• Safety Statements: 26-37/39-24/25
• WGK Germany: 2
• RTECS: UX9660500
• HS Code: 29339900
• Hazardous Substances Data: 7491-74-9(Hazardous Substances Data)
• Toxicity: LD50 oral in mouse: 2gm/kg