Aniracetam , ≥98.0%(GC) , 72432-10-1

Synonym(s):
1-(4-Methoxybenzoyl)-2-pyrrolidinone;1-(4-methoxybenzoyl)pyrrolidin-2-one, Draganon, Sarpul, Ampamet, Memodrin, Referan;Aniracetam - CAS 72432-10-1 - Calbiochem;Memodrin, Referan, 1-(4-methoxybenzoyl)pyrrolidin-2-one, Draganon, Sarpul, Ampamet;Ro 13-5057

CAS NO.：72432-10-1

Empirical Formula: C12H13NO3

Molecular Weight: 219.24

MDL number: MFCD00153767

EINECS: 615-758-3

PRODUCT Properties

• Melting point: 121-122?C
• Boiling point: 399.7±34.0 °C(Predicted)
• Density: 1.236±0.06 g/cm3(Predicted)
• storage temp.: Sealed in dry,Room Temperature
• solubility: Chloroform (Slightly), Methanol (Slightly)
• pka: -1.74±0.20(Predicted)
• form: Solid
• color: White
• Water Solubility: Soluble in chloroform. Also soluble in ethanol. Insoluble in water
• Merck: 14,662
• InChI: InChI=1S/C12H13NO3/c1-16-10-6-4-9(5-7-10)12(15)13-8-2-3-11(13)14/h4-7H,2-3,8H2,1H3
• InChIKey: ZXNRTKGTQJPIJK-UHFFFAOYSA-N
• SMILES: N1(C(=O)C2=CC=C(OC)C=C2)CCCC1=O

Description and Uses

Aniracetam, also known as N-anisoyl-2-pyrrolidinone, together with piracetam and nefiracetam, belong to the same class of piracetam metabolized drugs of brain cells. It is a non-NMDA receptor agent useful for the treatment of cognitive impairment. These drugs can enhance the activity of synaptic neurons phospholipase, increase the ATP formation and transport in brain, increase protein synthesis and RNA, promote the usage of brain on amino acids, phospholipids, glucose and oxygen, increase the patient's response, excitability and memory. Aniracetam has a higher effect than piracetam, but with a relatively minor side effect. It is well tolerated and efficacious in improving velocity and accuracy of the saccades, complex reaction time, and other aspects of performance.

Aniracetam is AMPA receptor potentiator with Cognition enhancer related to Piracetam. It is used as a nootropic drug to ameliorate memory and attention disturbances accompanying cerebrovascular diseases and degenerative brain disorders. Compound with anti-depressive properties used as a mental performance enhancer. Slows the rate of ion-channel closing.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H303
• Precautionary statements: P270-P301+P312-P403-P501c
• WGK Germany: 2
• RTECS: UY5781900
• HS Code: 2933.79.1500
• Toxicity: LD50 in rats, mice (mg/kg): ~4500, >5000 orally (Cumin)