4-Hydroxy-2-oxopyrrolidine-N-acetamide , 10mMinDMSO , 62613-82-5
Synonym(s):
4-Hydroxy-2-oxopyrrolidine-N-acetamide
CAS NO.：62613-82-5
Empirical Formula: C6H10N2O3
Molecular Weight: 158.16
MDL number: MFCD00242951
EINECS: 636-370-0
| Pack Size | Price | Stock | Quantity |
| 1ml | RMB399.20 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 165-168 °C |
| Boiling point: | 494.6±40.0 °C(Predicted) |
| Density | 1.416 |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly, Heated), Methanol (Slightly, Heated) |
| form | Solid |
| pka | 13.76±0.20(Predicted) |
| color | White to Off-White |
| Merck | 14,6942 |
| InChI | InChI=1S/C6H10N2O3/c7-5(10)3-8-2-4(9)1-6(8)11/h4,9H,1-3H2,(H2,7,10) |
| InChIKey | IHLAQQPQKRMGSS-UHFFFAOYSA-N |
| SMILES | N1(CC(N)=O)CC(O)CC1=O |
Description and Uses
Oxiracetam is a structural analogue of piracetam. This compound has enhancing effects on vigilance and memory. In comparison with piracetam, oxiracetam exhibits greater improvement in memory (Itil et al., 1986) and has been used extensively for the treatment of dementia, including AD, VaD, MID (Baumel et al., 1989; Dysken et al., 1989), and mixed forms. Green et al. (1992) failed to demonstrate a difference from placebo in AD patients. In contrast, Maina et al. (1989) studied 289 patients with MID in a double-blind placebo-controlled trial and after 12 weeks of treatment found that oxiracetam reduced behavioural symptoms.
Oxiracetam is a 4-hydroxy analog of piracetam with psychostimulant activity, reportedly useful in relieving the symptoms of cerebral insufficiency in the elderly.
