Vigabatrin , ≥98% , 60643-86-9

Synonym(s):
(±)-γ-Vinyl-GABA;(±)-4-Aminohexenoic acid;(±)-Vigabatrin;(R,S)-4-Amino-5-hexenoic acid

CAS NO.：60643-86-9

Empirical Formula: C6H11NO2

Molecular Weight: 129.16

MDL number: MFCD00274577

EINECS: 637-414-1

PRODUCT Properties

• Melting point: 209°
• Flash point: 9℃
• storage temp.: Desiccate at +4°C
• solubility: Freely soluble in water, slightly soluble in methanol, practically insoluble in methylene chloride.
• CAS DataBase Reference: 60643-86-9(CAS DataBase Reference)

Description and Uses

Vigabatrin, the gamma-vinyl derivative of GABA, is a new anticonvulsant reportedly effective in the treatment of intractable seizures unresponsive to currently available therapy. Mechanistically vigabatrin is a potent irreversible GABA aminotransferase inhibitor which modifies the enzyme's active-site by Michael addition. Other potential indications have been suggested for vigabatrin, including depression and schizophrenia.

antibiotic

Safety

• Symbol(GHS): GHS02,GHS06,GHS08
• Signal word: Danger
• Hazard statements: H225-H301+H311+H331-H370
• Precautionary statements: P210-P260-P280-P301+P310-P311
• Hazard Codes: Xi,T,F
• Risk Statements: 36/37/38-39/23/24/25-23/24/25-11
• Safety Statements: 26-36-45-36/37-16-7
• RIDADR: UN1230 - class 3 - PG 2 - Methanol, solution
• WGK Germany: 2
• RTECS: MP7745000
• Toxicity: LD50 i.p. in mice: >2500 mg/kg (Lscher)