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A8473212

Zonisamide , >98.0%(HPLC)(N) , 68291-97-4

Synonym(s):
1,2-Benzisoxazole-3-methanesulfonamide;AD 810, CI 912;Zonisamide - CAS 68291-97-4 - Calbiochem

CAS NO.:68291-97-4

Empirical Formula: C8H8N2O3S

Molecular Weight: 212.23

MDL number: MFCD00865316

EINECS: 614-395-8

Pack Size Price Stock Quantity
200MG RMB108.00 In Stock
1G RMB219.20 In Stock
5g RMB301.60 In Stock
25g RMB779.20 In Stock
100g RMB2271.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 275°C dec.
Boiling point: 223°C (rough estimate)
Density  1.4306 (rough estimate)
refractive index  1.5690 (estimate)
Flash point: 9℃
storage temp.  Keep in dark place,Sealed in dry,2-8°C
solubility  H2O: >5 mg/mL, soluble
form  solid
pka 10.2(at 25℃)
color  off-white
Merck  14,10192
InChIKey UBQNRHZMVUUOMG-UHFFFAOYSA-N
CAS DataBase Reference 68291-97-4(CAS DataBase Reference)

Description and Uses

Zonisamide is a broad-spectrum antiepileptic effective in the treatment of refractory seizures. In cultured spinal cord neurons, zonisamide blocks the sustained firing of action potentials induced by depolarizing steps of current injected across the membrane.

For use as adjunctive treatment of partial seizures in adults with epilepsy.

Safety

Symbol(GHS) 
GHS07,GHS08
Signal word  Warning
Hazard statements  H302-H361
Precautionary statements  P280-P301+P312+P330
Hazard Codes  Xn,T,F
Risk Statements  22-39/23/24/25-23/24/25-11
Safety Statements  7-16-36/37-45
RIDADR  UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany  3
RTECS  DE4930000
HS Code  2935904000
Hazardous Substances Data 68291-97-4(Hazardous Substances Data)
Toxicity LD50 in mice, rats (mg/kg): 1892, 2001 orally; 1273, 2569 s.c.; 699, 733 i.p.; 604, 748 i.v. (Masuda, 1980)

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