A8473212
Zonisamide , >98.0%(HPLC)(N) , 68291-97-4
Synonym(s):
1,2-Benzisoxazole-3-methanesulfonamide;AD 810, CI 912;Zonisamide - CAS 68291-97-4 - Calbiochem
CAS NO.:68291-97-4
Empirical Formula: C8H8N2O3S
Molecular Weight: 212.23
MDL number: MFCD00865316
EINECS: 614-395-8
Pack Size | Price | Stock | Quantity |
200MG | RMB108.00 | In Stock |
|
1G | RMB219.20 | In Stock |
|
5g | RMB301.60 | In Stock |
|
25g | RMB779.20 | In Stock |
|
100g | RMB2271.20 | In Stock |
|
others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
Melting point: | 275°C dec. |
Boiling point: | 223°C (rough estimate) |
Density | 1.4306 (rough estimate) |
refractive index | 1.5690 (estimate) |
Flash point: | 9℃ |
storage temp. | Keep in dark place,Sealed in dry,2-8°C |
solubility | H2O: >5 mg/mL, soluble |
form | solid |
pka | 10.2(at 25℃) |
color | off-white |
Merck | 14,10192 |
InChIKey | UBQNRHZMVUUOMG-UHFFFAOYSA-N |
CAS DataBase Reference | 68291-97-4(CAS DataBase Reference) |
Description and Uses
Zonisamide is a broad-spectrum antiepileptic effective in the treatment of refractory seizures. In cultured spinal cord neurons, zonisamide blocks the sustained firing of action potentials induced by depolarizing steps of current injected across the membrane.
For use as adjunctive treatment of partial seizures in adults with epilepsy.
Safety
Symbol(GHS) | GHS07,GHS08 |
Signal word | Warning |
Hazard statements | H302-H361 |
Precautionary statements | P280-P301+P312+P330 |
Hazard Codes | Xn,T,F |
Risk Statements | 22-39/23/24/25-23/24/25-11 |
Safety Statements | 7-16-36/37-45 |
RIDADR | UN1230 - class 3 - PG 2 - Methanol, solution |
WGK Germany | 3 |
RTECS | DE4930000 |
HS Code | 2935904000 |
Hazardous Substances Data | 68291-97-4(Hazardous Substances Data) |
Toxicity | LD50 in mice, rats (mg/kg): 1892, 2001 orally; 1273, 2569 s.c.; 699, 733 i.p.; 604, 748 i.v. (Masuda, 1980) |