Home Categories Biochemical Engineering 2,2'-O-Cyclouridine
A7705058

2,2'-O-Cyclouridine , 10mMinDMSO , 3736-77-4

CAS NO.:3736-77-4

Empirical Formula: C9H10N2O5

Molecular Weight: 226.19

MDL number: MFCD00004945

EINECS: 223-107-6

Pack Size Price Stock Quantity
1ml RMB399.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 248-251 °C(lit.)
alpha  -21°(19℃, c=4, H2O)
Boiling point: 456.3±55.0 °C(Predicted)
Density  2.01±0.1 g/cm3(Predicted)
refractive index  -20 ° (C=4, H2O)
storage temp.  -20°C
solubility  DMSO:2.0(Max Conc. mg/mL);8.84(Max Conc. mM)
PBS (pH:7.2):1.0(Max Conc. mg/mL);4.42(Max Conc. mM)
form  powder to crystal
pka 12.55±0.40(Predicted)
color  White to Almost white
optical activity [α]19/D 21°, c = 4 in H2O
InChI InChI=1S/C9H10N2O5/c12-3-4-6(14)7-8(15-4)11-2-1-5(13)10-9(11)16-7/h1-2,4,6-8,12,14H,3H2/t4-,6-,7+,8-/m1/s1
InChIKey UUGITDASWNOAGG-CCXZUQQUSA-N
SMILES C12O[C@@]3([H])[C@H](O)[C@@H](CO)O[C@@]3([H])N1C=CC(=O)N=2
CAS DataBase Reference 3736-77-4

Description and Uses

2,2'-Anhydro-1(B-D-arabinofuranosyl)uracil is a research tool for anticancer and antiviral studies. This works by inhibiting uridine phosphorylase, a key enzyme targeted by some antitumor drugs.

Research tool for antiviral and anticancer studies.1

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312+P330-P501
Safety Statements  24/25
WGK Germany  3
HS Code  29349990

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