A7133712
Rolipram , ≥97% , 61413-54-5
Synonym(s):
4-[3-(Cyclopentyloxy)-4-methoxyphenyl]-2-pyrrolidinone;Rolipram - CAS 61413-54-5 - Calbiochem;ZK 62711
CAS NO.：61413-54-5
Empirical Formula: C16H21NO3
Molecular Weight: 275.34
MDL number: MFCD00270906
EINECS: 262-771-1
| Pack Size | Price | Stock | Quantity |
| 10MG | RMB31.20 | In Stock |
|
| 50MG | RMB63.20 | In Stock |
|
| 100mg | RMB102.40 | In Stock |
|
| 250MG | RMB192.00 | In Stock |
|
| 500mg | RMB332.80 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 127-133 °C |
| Boiling point: | 418.29°C (rough estimate) |
| Density | 1.0677 (rough estimate) |
| refractive index | 1.5500 (estimate) |
| storage temp. | Sealed in dry,Store in freezer, under -20°C |
| solubility | H2O: 0.2 mg/mL |
| form | solid |
| pka | 16.02±0.40(Predicted) |
| color | white to off-white |
| Merck | 14,8251 |
| Stability: | Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months. |
Description and Uses
Rolipram (61413-54-5) is a selective inhibitor of cAMP-specific phosphodiesterase (PDE4), IC50 = 1 μM. Displays beneficial effects in neurodegenerative diseases. Rolipram also displays anti-inflammatory activity and synergizes with forskolin (cat.# 10-2073). Cell permeable.
(±)-Rolipram is a cAMP-specific phosphodiesterase 4 (PDE4) inhibitor.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38-11 |
| Safety Statements | 26-36 |
| RIDADR | 3249 |
| WGK Germany | 3 |
| RTECS | UY5749237 |
| HazardClass | 6.1(b) |
| PackingGroup | III |
| HS Code | 29337900 |
| Toxicity | LD50 oral in mouse: > 300mg/kg |
