A7022158
Calpeptin , 10mMinDMSO , 117591-20-5
Synonym(s):
Benzyloxycarbonylleucyl-norleucinal;Calpeptin - CAS 117591-20-5 - Calbiochem;N-Benzyloxycarbonyl-L-leucylnorieucinal;Z-Leu-Nle-CHO
Pack Size | Price | Stock | Quantity |
1ml | RMB551.20 | In Stock |
|
others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
Melting point: | 60-75 °C |
Boiling point: | 494.07°C (rough estimate) |
Density | 1.1667 (rough estimate) |
refractive index | 1.6800 (estimate) |
storage temp. | -20°C |
solubility | Soluble in DMSO at 15mg/ml |
form | White to off-white solid |
pka | 11.14±0.46(Predicted) |
color | white to beige |
InChIKey | PGGUOGKHUUUWAF-ROUUACIJSA-N |
CAS DataBase Reference | 117591-20-5(CAS DataBase Reference) |
Description and Uses
Calpeptin is used to to inhibit the activities of cathepsin L and calpain-1. Calpeptin blocked the expression of aspartyl protease cathepsin D, amyloid precursor protein, and calparin. It acts as an inhibitor of the Ca2+-dependent protease, calpain. Prevents collagen- and thrombin-induced platelet aggregation, probably by blocking calpain induced phospholipase C and thromboxane synthase activation. Potent cathepsin L inhibitor. It is shown to preferentially inhibit a subset of protein-tyrosine phosphatases.
Safety
Symbol(GHS) | GHS07 |
Signal word | Warning |
Hazard statements | H302-H315-H319-H335 |
Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 |
Safety Statements | 24/25 |
WGK Germany | 3 |
HS Code | 29242990 |