A7022158
Calpeptin , 10mMinDMSO , 117591-20-5
Synonym(s):
Benzyloxycarbonylleucyl-norleucinal;Calpeptin - CAS 117591-20-5 - Calbiochem;N-Benzyloxycarbonyl-L-leucylnorieucinal;Z-Leu-Nle-CHO
| Pack Size | Price | Stock | Quantity |
| 1ml | RMB551.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 60-75 °C |
| Boiling point: | 494.07°C (rough estimate) |
| Density | 1.1667 (rough estimate) |
| refractive index | 1.6800 (estimate) |
| storage temp. | -20°C |
| solubility | Soluble in DMSO at 15mg/ml |
| pka | 11.14±0.46(Predicted) |
| form | White to off-white solid |
| color | white to beige |
| InChIKey | PGGUOGKHUUUWAF-ROUUACIJSA-N |
Description and Uses
Calpeptin is used to to inhibit the activities of cathepsin L and calpain-1. Calpeptin blocked the expression of aspartyl protease cathepsin D, amyloid precursor protein, and calparin. It acts as an inhibitor of the Ca2+-dependent protease, calpain. Prevents collagen- and thrombin-induced platelet aggregation, probably by blocking calpain induced phospholipase C and thromboxane synthase activation. Potent cathepsin L inhibitor. It is shown to preferentially inhibit a subset of protein-tyrosine phosphatases.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 |
| Safety Statements | 24/25 |
| WGK Germany | 3 |
| HS Code | 29242990 |
