A6791212
PCI-34051 , ≥98% , 950762-95-5
| Pack Size | Price | Stock | Quantity |
| 10MG | RMB824.80 | In Stock |
|
| 50MG | RMB3424.00 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Density | 1.25 |
| storage temp. | Sealed in dry,Store in freezer, under -20°C |
| solubility | insoluble in H2O; insoluble in EtOH; ≥14.8 mg/mL in DMSO |
| form | Powder |
| pka | 9.16±0.30(Predicted) |
| color | White to gray |
Description and Uses
PCI-34051 is a potent, histone deacetylase 8 (HDAC8)-specific inhibitor. PCI-34051 induces caspase-dependent apoptosis in cell lines derived from T-cell lymphomas or leukemias. PCI-34051 did not affect other hematopoietic or solid tumor lines. PCI-34051 treatment has been shown to significantly reduce cholesterol accumulation in Niemann-Pick type C1 gene mutated human fibroblast.
