Ifosfamide , Medicinal grade , 3778-73-2

Synonym(s):
Ifex;Ifosfamide;N,3-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine-2-oxide

CAS NO.：3778-73-2

Empirical Formula: C7H15Cl2N2O2P

Molecular Weight: 261.09

MDL number: MFCD00057374

EINECS: 223-237-3

PRODUCT Properties

• Melting point: 48°C
• Boiling point: 336.1±52.0 °C(Predicted)
• Density: 1.33±0.1 g/cm3(Predicted)
• storage temp.: Inert atmosphere,2-8°C
• solubility: DMF:50.0(Max Conc. mg/mL);191.51(Max Conc. mM); DMSO:44.0(Max Conc. mg/mL);168.53(Max Conc. mM); Ethanol:51.0(Max Conc. mg/mL);195.34(Max Conc. mM); PBS (pH 7.2):10.0(Max Conc. mg/mL);38.3(Max Conc. mM); Water:52.0(Max Conc. mg/mL);199.17(Max Conc. mM)
• form: Solid
• pka: 1.44±0.20(Predicted)
• color: White to off-white

Description and Uses

Ifosphamide USP (Ifex)is used to treat germ cell testicular cancer; used in combination with mesna.

Safety

• Symbol(GHS): GHS06,GHS08
• Signal word: Danger
• Hazard statements: H301-H319-H340-H350-H360
• Precautionary statements: P201-P301+P310+P330-P305+P351+P338
• Hazard Codes: T
• Risk Statements: 25-36
• Safety Statements: 26-45
• RIDADR: 3249
• WGK Germany: 3
• RTECS: RP6050000
• HazardClass: 6.1(b)
• PackingGroup: III
• HS Code: 29349990
• Toxicity: LD50 in rats (mg/kg): 160 i.p. (Arnold, 1973); also reported as 150 i.p. (Brock)