A6815812
PJ34 HCl , ≥97% , 344458-15-7
| Pack Size | Price | Stock | Quantity |
| 5MG | RMB176.80 | In Stock |
|
| 25MG | RMB559.20 | In Stock |
|
| 100MG | RMB1543.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| solubility | H2O: soluble22mg/mL |
| form | White solid |
| color | white to yellow |
| Sensitive | Light Sensitive & Hygroscopic |
| Stability: | Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 3 months. |
Description and Uses
PJ-34 HCl (344458-15-7) is a potent and selective inhibitor of PARP1 and 2. EC50 = 20 nM.1?Reduces ischemia reperfusion injury in a mouse model.2 Displays anti-inflammatory effects in a transient focal cerebral ischemia mouse model.3 PJ-34 HCl causes PARP1 independent, p21 dependent mitotic arrest.4
A poly adenosine diphosphate-ribose polymerase inhibitor, attenuates chromate-induced nephrotoxicity. PJ-34 has a lethal effect on breast cancer cells, both in vitro and in vivo, in particular on breast cancer MCF-7.
Safety
| Safety Statements | 22-24/25 |
| WGK Germany | 3 |
| HS Code | 29339900 |
