A1429550
ABT-263 , ≥98% , 923564-51-6
CAS NO.：923564-51-6
Empirical Formula: C47H55ClF3N5O6S3
Molecular Weight: 974.61
MDL number: MFCD12756219
| Pack Size | Price | Stock | Quantity |
| 5mg | RMB319.20 | In Stock |
|
| 25mg | RMB1119.20 | In Stock |
|
| 100mg | RMB2239.20 | In Stock |
|
| 500mg | RMB6399.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 114-116°C |
| Density | 1.41±0.1 g/cm3(Predicted) |
| storage temp. | -20°C Freezer, Under Inert Atmosphere |
| solubility | Soluble in DMSO (up to 25 mg/ml). |
| form | solid |
| pka | 4.60±0.10(Predicted) |
| color | White |
| Stability: | Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months. |
Description and Uses
ABT-263 (923564-51-6) is a potent and selective Bcl-2 family inhibitor / BH3 domain mimetic which binds to Bcl-2, Bcl-xL?and Bcl-w (Ki<1 nM). A useful tool compound which has shown interesting results in various cancer clinical trials.2?Synergizes with deoxyglucose and other agents, inducing apoptosis in cancer cells in a xenograft mouse model.3?A novel senolytic agent, inducing apoptosis preferentially in senescent cells in a cell type-restricted manner.4
A novel inhibitor of antiapoptotic BCL-2 proteins; a new promising anticancer drug candidate.
Safety
| HS Code | 29339900 |
