Indirubin , Analysis of standard products, ≥98% , 479-41-4

Synonym(s):
Coroupitine B;Indigo Red;Indigopurpurin

CAS NO.：479-41-4

Empirical Formula: C16H10N2O2

Molecular Weight: 262.26

MDL number: MFCD00221745

EINECS: 610-392-0

PRODUCT Properties

• Melting point: 350°C(lit.)
• Boiling point: 496.6±45.0 °C(Predicted)
• Density: 1.417±0.06 g/cm3(Predicted)
• storage temp.: -20°C
• solubility: DMSO (Slightly), Methanol (Very Slightly, Heated)
• pka: 9.13±0.20(Predicted)
• form: Purple powder.
• color: Very Dark Red
• λmax: 540nm(DMSO)(lit.)
• InChI: InChI=1S/C16H10N2O2/c19-15-10-6-2-4-8-12(10)17-14(15)13-9-5-1-3-7-11(9)18-16(13)20/h1-8,17H,(H,18,20)
• InChIKey: CRDNMYFJWFXOCH-UHFFFAOYSA-N
• SMILES: N1C2=C(C=CC=C2)C(=C2C(=O)C3=C(N2)C=CC=C3)C1=O
• CAS DataBase Reference: 479-41-4(CAS DataBase Reference)

Description and Uses

A further alkaloid isolated from the matured fruit of Couroupita guianensis, this base forms red crystals from EtOH and melts above 340°C. It forms the Nacetyl derivative, m.p. 186°C. The full structure has not yet been established.

Indigopurpurin is a purple 3,2-bisindole derivative and was shown to exhibit inhibitory allergic contact dermatitis via regulating T helper (Th)-mediated immune system in DNCB-induced model. A possible glycogen synthase kinase-3 (GSK-3) inhibitor the active component of a traditional Congolese antiepilepsy treatment.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H319-H335-H315
• Precautionary statements: P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362
• RTECS: DU2995000
• HS Code: 29339900