Home Categories API 5-Iodo-2′-deoxyuridine
A4974512

5-Iodo-2′-deoxyuridine , 99% , 54-42-2

Synonym(s):
Idoxuridine;IDU;5-Iodo-2′-deoxyuridine;5-IUdR;IdUrd

CAS NO.:54-42-2

Empirical Formula: C9H11IN2O5

Molecular Weight: 354.1

MDL number: MFCD00134656

EINECS: 200-207-8

Pack Size Price Stock Quantity
1G RMB42.40 In Stock
5G RMB150.40 In Stock
25G RMB677.60 In Stock
100g RMB2631.20 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 194 °C (lit.)
alpha  280 º (c=1,1M NaOH)
Density  1.7911 (estimate)
refractive index  30 ° (C=1, 1mol/L NaOH)
storage temp.  2-8°C
solubility  DMSO (Slightly, Sonicated), Methanol (Slightly, Heated, Sonicated)
form  Crystalline Powder
pka 8.25(at 25℃)
color  White to slightly beige
Water Solubility  1.6 g/L (20 ºC)
Sensitive  Air & Light Sensitive
Merck  14,4891
BRN  30397
InChIKey XQFRJNBWHJMXHO-FSDSQADBSA-N

Description and Uses

5-Iodo-2'-deoxyuridine is a nucleoside analog that inhibits the replication of viruses and other DNA-containing organisms. 2'-Deoxy-5-iodouridine also has inhibitory properties on cell nuclei, which may be due to its ability to bind with DNA and prevent the synthesis of RNA or protein.

Idoxuridine is an antiviral agent effective against herpes-simplex infections; in ophthalmie eyedrops, ointments, and solutions.

Safety

Symbol(GHS) 
GHS07,GHS08
Signal word  Warning
Hazard statements  H315-H319-H335-H341-H361
Precautionary statements  P201-P302+P352-P305+P351+P338-P308+P313
Hazard Codes  T,Xn
Risk Statements  45-46-61-40-68-62-36/37/38-63
Safety Statements  53-45-36-22-36/37-26
WGK Germany  3
RTECS  YU7700000
8-23
TSCA  Yes
HS Code  29389090
Toxicity LD50 i.p. in mice: 2.5 g/kg (Prusoff, 1979)

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