Uracil , 99%, for cell culture , 66-22-8
Synonym(s):
2,4(1H,3H)-Pyrimidinedione;2,4-Dihydroxypyrimidine;2,4-Pyrimidinediol;Uracil
CAS NO.：66-22-8
Empirical Formula: C4H4N2O2
Molecular Weight: 112.09
MDL number: MFCD00006016
EINECS: 200-621-9
| Pack Size | Price | Stock | Quantity |
| 25G | RMB59.20 | In Stock |
|
| 100G | RMB164.00 | In Stock |
|
| 500g | RMB501.60 | In Stock |
|
| 2.5kg | RMB1823.20 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | >300 °C (lit.) |
| Boiling point: | 209.98°C (rough estimate) |
| Density | 1.4421 (rough estimate) |
| refractive index | 1.4610 (estimate) |
| storage temp. | 2-8°C |
| solubility | Aqueous Acid (Slightly), DMSO (Slightly, Heated, Sonicated), Methanol (Slightly) |
| form | Crystalline Powder |
| pka | 9.45(at 25℃) |
| color | White to slightly yellow |
| Water Solubility | SOLUBLE IN HOT WATER |
| Merck | 14,9850 |
| BRN | 606623 |
| Stability: | Stable. Incompatible with strong oxidizing agents. |
| InChIKey | ISAKRJDGNUQOIC-UHFFFAOYSA-N |
| LogP | -1.037 (est) |
| CAS DataBase Reference | 66-22-8(CAS DataBase Reference) |
| NIST Chemistry Reference | Uracil(66-22-8) |
| EPA Substance Registry System | Uracil (66-22-8) |
Description and Uses
Uracil is a pyrimidine base and a fundamental component of RNA where it binds to adenine via hydrogen bonds. It is converted into the nucleoside uridine through the addition of a ribose moiety, then to the nucleotide uridine monophosphate by the addition of a phosphate group.
Uracil metabolism levels may serve as a diagnostic for oral cancer. It was shown that measuring the overproduction of the metabolite uracil improves the diagnosis and prognosis of gingival buccal squamous cell carcinoma, one of the most common oral cancers in India. And about 83.09% of the tumour tissues showed significant changes in both uracil and pyrimidine metabolism. Higher levels of uracil in patients with lymph node metastases suggest that the metabolites may increase the cancer's ability to spread. It could also be used as a marker for recurrence follow-up, the researchers said.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315-H319 |
| Precautionary statements | P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 |
| Hazard Codes | Xi |
| Safety Statements | 22-24/25 |
| WGK Germany | 2 |
| RTECS | YQ8650000 |
| TSCA | Yes |
| HS Code | 29335990 |
