Cordycepin , 98% , 73-03-0

Synonym(s):
3′-Deoxyadenosine

CAS NO.：73-03-0

Empirical Formula: C10H13N5O3

Molecular Weight: 251.24

MDL number: MFCD00037998

EINECS: 200-791-4

PRODUCT Properties

• Melting point: 225-229 °C
• alpha: D20 -47°; D27 -42°
• Boiling point: 394.4°C (rough estimate)
• Density: 1.2938 (rough estimate)
• refractive index: 1.7610 (estimate)
• storage temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
• solubility: Soluble in DMSO (up to 25 mg/ml).
• form: Powder
• pka: 13?+-.0.60(Predicted)
• color: White to Off-white
• λmax: 260nm(EtOH)(lit.)
• Merck: 14,2529
• BRN: 35194
• Stability: Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
• InChIKey: OFEZSBMBBKLLBJ-BAJZRUMYSA-N
• CAS DataBase Reference: 73-03-0(CAS DataBase Reference)
• EPA Substance Registry System: Adenosine, 3'-deoxy- (73-03-0)

Description and Uses

Cordycepin (73-03-0) is an adenosine analog lacking the hydroxyl at the 3’ position. Inhibits PARP1?and polyadenylation2. Displays anti-inflammatory effects1,3?and neuroprotective effects by inhibiting Aβ-induced apoptosis in hippocampal neurons4. Induces apoptosis in a variety of cancer cell lines5. Displays antiobesity effects.6?Inhibits cell senescence via activation of AMPK.7?Maintains stem cell pluripotency and increases iPS cell generation efficiency.8

First reported nucleoside antibiotic.

Safety

• Symbol(GHS): GHS06
• Signal word: Danger
• Hazard statements: H301+H311+H331
• Precautionary statements: P280-P301+P310+P330-P302+P352+P312-P304+P340+P311
• Hazard Codes: Xn,T
• Risk Statements: 40-36/37/38-25-20/21/22
• Safety Statements: 22-36-45-26
• RIDADR: UN 2811
• WGK Germany: 3
• RTECS: AU7358610
• F: 10-21
• HazardClass: 6.1
• HS Code: 29349990