Adenosine 3′,5′-cyclic monophosphate(cAMP) , 99% , 60-92-4

CAS NO.：60-92-4

Empirical Formula: C10H12N5O6P

Molecular Weight: 329.21

MDL number: MFCD00005845

EINECS: 200-492-9

PRODUCT Properties

• Melting point: 260 °C (dec.)(lit.)
• alpha: -53.7 º (c=0.7,water)
• Boiling point: 56.12°C
• Density: 2.47±0.1 g/cm3(Predicted)
• storage temp.: -20°C
• solubility: H₂O: 10 mg/mL pH of aqueous solution is approx. 3.0. The sodium salt (A6885) is about 20×
• form: powder
• pka: 1.00±0.60(Predicted)
• color: white
• Water Solubility: 50 mg/mL
• Merck: 14,2708
• BRN: 52645
• Stability: Hygroscopic
• NIST Chemistry Reference: Adenosine 3',5'-cyclic monophosphate(60-92-4)
• EPA Substance Registry System: Adenosine, cyclic 3',5'-(hydrogen phosphate) (60-92-4)

Description and Uses

cAMP is used for intracellular signal transduction in many different organisms, conveying the cAMP-dependent pathway. Restoration of several morphological characteristics of normal fibroblasts in sarcoma cells when treated with adenosine-3': 5'-cyclic monophosphate. In the presence of adenosine 3':5'-cyclic monophosphate, protein kinase I dissociated into two subunits: a subunit binding adenosine 3':5'-cyclic monophosphate, and a catalytic subunit. Stimulation of calcium uptake in platelet membrane vesicles by adenosine 3',5'-cyclic monophosphate.

Safety

• Symbol(GHS): GHS05
• Signal word: Danger
• Hazard statements: H314
• Precautionary statements: P264b-P280-P301+P330+P331-P304+P340-P305+P351+P338-P310-P363-P403+P233-P501c
• Hazard Codes: C,Xi
• Risk Statements: 34-36/37/38
• Safety Statements: 22-24/25-45-36/37/39-26-36
• WGK Germany: 3
• RTECS: AU7357600
• F: 10-21
• TSCA: Yes
• HS Code: 29349990
• Toxicity: oms-hmn:oth 100 mmol/L JIDEAE 65,52,75