2'-Deoxyadenosine monohydrate , ≥99.0%(HPLC) , 16373-93-6

Synonym(s):
9-(2-Deoxy-β-D-ribofuranosyl)adenine;Adenine deoxyriboside

CAS NO.：16373-93-6

Empirical Formula: C10H15N5O4

Molecular Weight: 269.26

MDL number: MFCD00149364

EINECS: 683-408-7

PRODUCT Properties

• Melting point: 187-189 °C
• refractive index: -25.5 ° (C=0.5, H2O)
• storage temp.: 2-8°C
• solubility: H2O: soluble50mg/mL, clear, colorless
• form: powder
• color: White to light beige
• Water Solubility: 0.3 g/100 mL (20 ºC)
• BRN: 5191174
• Stability: Stable, but air sensitive. Incompatible with strong oxidizing agents.
• InChIKey: WZJWHIMNXWKNTO-VWZUFWLJSA-N

Description and Uses

2'-Deoxyadenosine monohydrate is an adenosine nucleotide, which can be synthesized by the enzyme adenosine kinase. 2'-Deoxyadenosine monohydrate is a competitive inhibitor of phosphodiesterase, which breaks down cyclic nucleotides to their corresponding monophosphate form. This leads to elevated levels of cAMP, which can cause neuronal death by apoptosis.

2'-Deoxyadenosineise is used by some cells as an energy source under energy stress conditions and to affect cAMP levels. 2'-dAdo is used in comparison studies of the functions of adenosine analogues on various biological processes.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302
• Precautionary statements: P264b-P270-P301+P312-P330-P403-P501c
• Hazard Codes: Xn,Xi
• Risk Statements: 22-36/37/38-20/21/22
• Safety Statements: 24/25-37/39-36-26
• RIDADR: UN2811 6.1/PG 3
• WGK Germany: 3
• RTECS: AU7358600
• F: 10-23
• TSCA: Yes
• HS Code: 29349990