coenzyme B12 , ≥98% , 13870-90-1

Synonym(s):
5′-Deoxyadenosylcobalamine;Adenosyl cobalamine;Cobamamide;DMBC coenzyme

CAS NO.：13870-90-1

Empirical Formula: C72H100CoN18O17P

Molecular Weight: 1579.58

MDL number: MFCD00135609

EINECS: 237-627-6

PRODUCT Properties

• storage temp.: -20°C
• solubility: DMSO (Slightly), Methanol (Slightly), Water (Slightly, Sonicated)
• form: Solid
• pka: 3.5(at 25℃)
• color: Red to Very Dark Red
• Water Solubility: 26g/L(24 ºC)
• Merck: 13,2476
• BRN: 4122932
• Stability: Hygroscopic
• InChIKey: WAJLPPDUWGAMTH-NGQUPMDYNA-L

Description and Uses

Coenzyme B12 (adenosylcobalamin; AdoCbl; 5'-Deoxyadenosylcobalamin) is a form of vitamin B12. It belongs to the corrinoid group of compounds containing a corrin macrocycle and are produced only by certain bacteria and archaea. It is a cofactor for various enzymes, including mutases, eliminases, aminomutases, and reductases. These enzymes catalyze reactions that generate free radicals through the release of the adenosyl group, allowing usually unreactive molecules to become reactive. Genetic mutations in enzymes synthesizing Coenzyme B12 lead to Coenzyme B12 deficiency and methylmalonic aciduria.

emulsifying agent

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H302-H315-H319-H335
• Precautionary statements: P261-P305+P351+P338
• Hazard Codes: Xi
• Risk Statements: 36/37/38
• Safety Statements: 22-24/25-36-26
• WGK Germany: 3
• RTECS: GG3800000
• F: 8
• HS Code: 2936260000
• Toxicity: LD50 oral in guinea pig: 5gm/kg