2-Amino-4-bromophenol , 98% , 40925-68-6

Synonym(s):
4-Bromo-2-aminophenol;NSC 523846

CAS NO.：40925-68-6

Empirical Formula: C6H6BrNO

Molecular Weight: 188.02

MDL number: MFCD00235171

EINECS: 627-173-0

PRODUCT Properties

• Melting point: 135-140°C
• Boiling point: 282.8±25.0 °C(Predicted)
• Density: 1.768±0.06 g/cm3(Predicted)
• storage temp.: 2-8°C
• form: powder to crystal
• pka: 9.19±0.18(Predicted)
• color: White to Gray to Brown
• BRN: 3236448
• InChI: InChI=1S/C6H6BrNO/c7-4-1-2-6(9)5(8)3-4/h1-3,9H,8H2
• InChIKey: JHRIPENGTGSNPJ-UHFFFAOYSA-N
• SMILES: C1(O)=CC=C(Br)C=C1N
• CAS DataBase Reference: 40925-68-6(CAS DataBase Reference)

Description and Uses

2-Amino-4-bromophenol is a reactant for the preparation of (aryl)oxadiazolobenzoxazinones via Suzuki-Miyaura reaction, copper-catalyzed oxidative amination of benzoxazoles and related azoles via C-H and C-N bond activation synthesis of N-(alkoxyphenyl)-aminocarbonylbenzoic acid derivatives as protein tyrosine phophatase 1B inhibitors,preparation of lipophilic deoxy-xylulose-phosphate reductoisomerase inhibitors,synthesis of benzoxazole benzenesulfonamides as allosteric inhibitors of fructose-1,6-bisphosphatase.

Reactant for:

• Preparation of (aryl)oxadiazolobenzoxazinones via Suzuki-Miyaura reaction
• Copper-catalyzed oxidative amination of benzoxazoles and related azoles via C-H and C-N bond activation
• Synthesis of N-(alkoxyphenyl)-aminocarbonylbenzoic acid derivatives as protein tyrosine phophatase 1B inhibitors
• Preparation of lipophilic deoxy-xylulose-phosphate reductoisomerase inhibitors
• Synthesis of benzoxazole benzenesulfonamides as allosteric inhibitors of fructose-1,6-bisphosphatase

Safety

• Symbol(GHS): GHS07,GHS08
• Signal word: Danger
• Hazard statements: H302-H315-H317-H319-H334-H335
• Precautionary statements: P261-P264-P280-P301+P312-P302+P352-P305+P351+P338
• Hazard Codes: Xi,Xn
• Risk Statements: 20/21/22-36/37/38-42/43-22
• Safety Statements: 26-36/37/39-36/37-22
• WGK Germany: 3
• HazardClass: IRRITANT
• HS Code: 29222990