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A0677812

Antipyrine , 99% , 60-80-0

Synonym(s):
2,3-Dimethyl-1-phenyl-3-pyrazolin-5-one;Antipyrine;Marenostrin;Phenazone;Phenazonum

CAS NO.:60-80-0

Empirical Formula: C11H12N2O

Molecular Weight: 188.23

MDL number: MFCD00003146

EINECS: 200-486-6

Pack Size Price Stock Quantity
100G RMB58.40 In Stock
500G RMB188.80 In Stock
2.5kg RMB804.80 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 109-111 °C(lit.)
Boiling point: 319 °C
Density  1,19 g/cm3
refractive index  1.5850 (estimate)
storage temp.  2-8°C
solubility  H2O: soluble1 gm in less than 1ml
form  Crystalline Powder
pka pKa 1.4 (Uncertain)
color  White
Water Solubility  1000 g/L (20 ºC)
Merck  14,716
BRN  157775
Stability: Stable. Incompatible with ammonia, strong acids, alkalies, strong oxidizing agents, metallic salts, phenol.
LogP 0.380

Description and Uses

Antipyrine has been used for immunoblotting. It has also been used as an internal reference marker for studying the transport characteristics of platinum-containing drug, cisplatin in the human placenta in vitro. Antipyrine is an analgesic and antipyretic that has been given by mouth and as ear drops. It is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P501
Hazard Codes  Xn
Risk Statements  22-36/37/38
Safety Statements  26-36-37/39
RIDADR  3249
WGK Germany  1
RTECS  CD2450000
10
TSCA  Yes
HazardClass  6.1(b)
PackingGroup  III
HS Code  29331190
Toxicity LD50 orally in rats: 1.8 g/kg (Hart)

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