T9992330
Tetrahydrofurfurylamine , >98.0%(GC)(T) , 4795-29-3
Synonym(s):
2-(Aminomethyl)tetrahydrofuran
CAS NO.：4795-29-3
Empirical Formula: C5H11NO
Molecular Weight: 101.15
MDL number: MFCD00005373
EINECS: 225-351-9
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 136 °C |
| Boiling point: | 153-154 °C744 mm Hg(lit.) |
| Density | 0.98 g/mL at 25 °C(lit.) |
| refractive index | n |
| Flash point: | 114 °F |
| storage temp. | Flammables area |
| solubility | Chloroform, Methanol |
| pka | 9.47±0.29(Predicted) |
| form | Liquid |
| color | Clear colorless to light yellow |
| explosive limit | 1.6-14.1%(V) |
| Water Solubility | miscible |
| Sensitive | Air Sensitive & Hygroscopic |
| BRN | 102729 |
| LogP | -0.348 (est) |
| CAS DataBase Reference | 4795-29-3(CAS DataBase Reference) |
| NIST Chemistry Reference | 2-Furanmethanamine, tetrahydro-(4795-29-3) |
| EPA Substance Registry System | Tetrahydrofurfurylamine (4795-29-3) |
Description and Uses
Tetrahydro-2-furanmethanamine is used in the synthesis of novel topoisomerase I targeting anti-cancer agents with mild to potent cytotoxic activity. Also used in the discovery and synthesis of orally bioavailable stearoyl-CoA desaturase 1 inhibitors
Safety
| Symbol(GHS) |   GHS02,GHS07 |
| Signal word | Warning |
| Hazard statements | H226-H315-H319 |
| Precautionary statements | P210-P302+P352-P305+P351+P338 |
| Hazard Codes | Xi |
| Risk Statements | 10-36/37/38 |
| Safety Statements | 26-36-37/39-16 |
| RIDADR | UN 2943 3/PG 3 |
| WGK Germany | 3 |
| RTECS | LV0175000 |
| TSCA | Yes |
| HazardClass | 3 |
| PackingGroup | III |
| HS Code | 29321900 |
