Tetrahydrofuran-2-carboxylic Acid , >98.0%(GC)(T) , 16874-33-2

Synonym(s):
Tetrahydrofuran-2-carboxylic acid

CAS NO.：16874-33-2

Empirical Formula: C5H8O3

Molecular Weight: 116.12

MDL number: MFCD00022473

EINECS: 605-530-1

PRODUCT Properties

• Melting point: 21°C
• Boiling point: 128-129 °C13 mm Hg(lit.)
• Density: 1.209 g/mL at 25 °C(lit.)
• refractive index: n20/D 1.46(lit.)
• Flash point: 139 °C
• storage temp.: Sealed in dry,2-8°C
• solubility: Chloroform (Slightly), Methanol (Slightly)
• pka: 3.60±0.20(Predicted)
• form: Liquid
• color: Clear yellow to brown
• Water Solubility: soluble
• BRN: 109671

Description and Uses

2-Tetrahydrofuroic acid is used as a reagent to synthesize Alfuzosin (HCl: A532000), an unselective alpha-1 blocker that is used to treat lower urinary tract symptoms and benign prostatic hyperplasia.

Safety

• Symbol(GHS): GHS05
• Signal word: Danger
• Hazard statements: H314
• Precautionary statements: P260-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338
• Hazard Codes: C
• Risk Statements: 22-34
• Safety Statements: 26-36/37/39-45-28A
• RIDADR: UN 3265 8/PG 3
• WGK Germany: 3
• HazardClass: 8
• PackingGroup: III
• HS Code: 29321900