Home Categories Inorganic chemistry Osmium tetroxide
S9779528

Osmium tetroxide , ≥99% , 20816-12-0

Synonym(s):
‘Osmic acid’;Osmium(VIII)-oxide

CAS NO.:20816-12-0

Empirical Formula: O4Os

Molecular Weight: 254.23

MDL number: MFCD00011150

EINECS: 244-058-7

Update time: 2022-07-08

PRODUCT Properties

Melting point: 40°C
Boiling point: 130 °C
Density  1.04
vapor density  8.8 (vs air)
vapor pressure  7 mmHg at 20 °C
Flash point: -40 °C
storage temp.  2-8°C
solubility  Soluble in alcohol, ether, chloroform, benzene, ammonium hydroxide, phosphorus oxychloride and carbon tetrachloride
form  Solution
color  White to yellow,or lemon yellow
Specific Gravity 5.10
Odor Acrid, chlorine-like odor detectable at 2 ppm (20 mg/m3)
Water Solubility  Soluble in chloroform, alcohol and ethers.Soluble in water, organic solvents, benzene, alcohol, ether, ammonium hydroxide, phosphorus oxychloride and carbon tetrachloride.
Sensitive  Air Sensitive
Merck  14,6893
crystal system Monoclinic
Space group C2/c
Lattice constant
a/nmb/nmc/nmα/oβ/oγ/oV/nm3
0.93790.45150.863290116.6900.3268

Stability: Stable. Incompatible with strong acids, hydrogen chloride, organic materials, finely powdered metals.
CAS DataBase Reference 20816-12-0(CAS DataBase Reference)
NIST Chemistry Reference Osmium tetraoxide(20816-12-0)
EPA Substance Registry System Osmium tetroxide (20816-12-0)

Description and Uses

Osmium tetroxide is used in histopathological laboratories to stain the adipose tissue and as a stabilizing agent in scanning electron microscopy. In the chemical industry, it is used as a catalyst in the organic synthesis, particularly as the oxidizing agent in olefin-to-glycol conversion (546, 567). In the past, osmium tetroxide in the form of aqueous solution was used in forensic medicine to examine fingerprints. Osmium tetroxide is also used in medicine to treat rheumatoid arthritis.

Safety

Symbol(GHS) 
GHS05,GHS06
Signal word  Danger
Hazard statements  H300+H310+H330-H314
Precautionary statements  P260-P270-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338
Hazard Codes  O,T,C,T+,F,Xi,Xn
Risk Statements  8-23/24/25-40-34-26/27/28-42/43-11-67-66-36/37/38-19-36/38-36/37
Safety Statements  17-26-27-36/37/39-45-7/9-36/37-16-28-23
OEB E
OEL TWA: 0.002 mg/m3 (0.0002 ppm), STEL: 0.006 mg/m3 (0.0006 ppm)
RIDADR  UN 3175 4.1/PG 2
WGK Germany  3
RTECS  RN1140000
TSCA  Yes
HazardClass  6.1
PackingGroup  I
HS Code  28439090
Hazardous Substances Data 20816-12-0(Hazardous Substances Data)
Toxicity LD50 oral (rat)
14 mg/kg
LCLO inhal (rat)
40 ppm (4 h)
PEL (OSHA)
0.0002 ppm (0.002 mg/m3)
TLV-TWA (ACGIH)
0.0002 ppm (0.002 mg/m3)
STEL (ACGIH)
0.0006 ppm (0.006 mg/m3)
IDLA 1 mg Os/m3

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